Sleep duration and risk of type 2 diabetes: a meta-analysis of prospective studies

Zhilei Shan; Hongfei Ma; Manling Xie; Peipei Yan; Yanjun Guo; Wei Bao; Ying Rong; Chandra L Jackson; Frank B Hu; Liegang Liu

doi:10.2337/dc14-2073

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Sleep duration and risk of type 2 diabetes: a meta-analysis of prospective studies

Journal article

Peer reviewed

Sleep duration and risk of type 2 diabetes: a meta-analysis of prospective studies

Zhilei Shan, Hongfei Ma, Manling Xie, Peipei Yan, Yanjun Guo, Wei Bao, Ying Rong, Chandra L Jackson, Frank B Hu and Liegang Liu

Diabetes care, Vol.38(3), pp.529-537

03/2015

DOI: 10.2337/dc14-2073

PMID: 25715415

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Abstract

It remains unclear how many hours of sleep are associated with the lowest risk of type 2 diabetes. This meta-analysis was performed to assess the dose-response relationship between sleep duration and risk of type 2 diabetes. PubMed and Embase were searched up to 20 March 2014 for prospective observational studies that assessed the relationship of sleep duration and risk of type 2 diabetes. Both semiparametric and parametric methods were used. Ten articles with 11 reports were eligible for inclusion in the meta-analysis. A total of 18,443 incident cases of type 2 diabetes were ascertained among 482,502 participants with follow-up periods ranging from 2.5 to 16 years. A U-shaped dose-response relationship was observed between sleep duration and risk of type 2 diabetes, with the lowest risk observed at a sleep duration category of 7-8 h per day. Compared with 7-h sleep duration per day, the pooled relative risks for type 2 diabetes were 1.09 (95% CI 1.04-1.15) for each 1-h shorter sleep duration among individuals who slept <7 h per day and 1.14 (1.03-1.26) for each 1-h increment of sleep duration among individuals with longer sleep duration. Our dose-response meta-analysis of prospective studies shows a U-shaped relationship between sleep duration and risk of type 2 diabetes, with the lowest type 2 diabetes risk at 7-8 h per day of sleep duration. Both short and long sleep duration are associated with a significantly increased risk of type 2 diabetes, underscoring the importance of appropriate sleep duration in the delay or prevention of type 2 diabetes.

Prospective Studies

Humans

Middle Aged

Risk Factors

Male

Diabetes Mellitus, Type 2 - epidemiology

Young Adult

Diabetes Mellitus, Type 2 - physiopathology

Time Factors

Adult

Diabetes Mellitus, Type 2 - etiology

Female

Aged

Sleep - physiology

Details

Title: Subtitle: Sleep duration and risk of type 2 diabetes: a meta-analysis of prospective studies
Creators: Zhilei Shan - Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China
Hongfei Ma - Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China
Manling Xie - Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China
Peipei Yan - Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China
Yanjun Guo - MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China
Wei Bao - Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China
Ying Rong - Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China
Chandra L Jackson - Harvard Medical School, Boston, MA
Frank B Hu - Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA lgliu@mails.tjmu.edu.cn frank.hu@channing.harvard.edu
Liegang Liu - Huazhong University of Science and Technology
Resource Type: Journal article
Publication Details: Diabetes care, Vol.38(3), pp.529-537
DOI: 10.2337/dc14-2073
PMID: 25715415
NLM abbreviation: Diabetes Care
ISSN: 0149-5992
eISSN: 1935-5548
Publisher: United States
Language: English
Date published: 03/2015
Academic Unit: Epidemiology; Fraternal Order of Eagles Diabetes Research Center
Record Identifier: 9983995179902771

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