Journal article
Sleep modulates word-pair learning but not motor sequence learning in healthy older adults
Neurobiology of aging, Vol.33(5), pp.991-1000
05/2012
DOI: 10.1016/j.neurobiolaging.2011.06.029
PMCID: PMC3307877
PMID: 22244090
Abstract
Sleep benefits memory across a range of tasks for young adults. However, remarkably little is known of the role of sleep on memory for healthy older adults. We used 2 tasks, 1 assaying motor skill learning and the other assaying nonmotor/declarative learning, to examine off-line changes in performance in young (20–34 years), middle-aged (35–50 years), and older (51–70 years) adults without disordered sleep. During an initial session, conducted either in the morning or evening, participants learned a motor sequence and a list of word pairs. Memory tests were given twice, 12 and 24 hours after training, allowing us to analyze off-line consolidation after a break that included sleep or normal wake. Sleep-dependent performance changes were reduced in older adults on the motor sequence learning task. In contrast, sleep-dependent performance changes were similar for all 3 age groups on the word pair learning task. Age-related changes in sleep or networks activated during encoding or during sleep may contribute to age-related declines in motor sequence consolidation. Interestingly, these changes do not affect declarative memory.
Details
- Title: Subtitle
- Sleep modulates word-pair learning but not motor sequence learning in healthy older adults
- Creators
- Jessica K Wilson - Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USABengi Baran - Department of Psychology and Neuroscience, University of Massachusetts, Amherst, Amherst, MA, USAEdward F Pace-Schott - Department of Psychology and Neuroscience, University of Massachusetts, Amherst, Amherst, MA, USARichard B Ivry - Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USARebecca M.C Spencer - Department of Psychology and Neuroscience, University of Massachusetts, Amherst, Amherst, MA, USA
- Resource Type
- Journal article
- Publication Details
- Neurobiology of aging, Vol.33(5), pp.991-1000
- DOI
- 10.1016/j.neurobiolaging.2011.06.029
- PMID
- 22244090
- PMCID
- PMC3307877
- NLM abbreviation
- Neurobiol Aging
- ISSN
- 0197-4580
- eISSN
- 1558-1497
- Publisher
- Elsevier Inc
- Grant note
- name: NIH, award: K99/R00AG029710; name: NIH, award: P01 NS040813
- Language
- English
- Date published
- 05/2012
- Academic Unit
- Psychiatry; Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984065475302771
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