Journal article
Sleep, plasticity, and sensory neurodevelopment
Neuron, Vol.110(20), pp.3230-3242
09/02/2022
DOI: 10.1016/j.neuron.2022.08.005
PMCID: PMC9588561
PMID: 36084653
Abstract
A defining feature of early infancy is the immense neural plasticity that enables animals to develop a brain that is functionally integrated with a growing body. Early infancy is also defined as a period dominated by sleep. Here, we describe three conceptual frameworks that vary in terms of whether and how they incorporate sleep as a factor in the activity-dependent development of sensory and sensorimotor systems. The most widely accepted framework is exemplified by the visual system where retinal waves seemingly occur independent of sleep-wake states. An alternative framework is exemplified by the sensorimotor system where sensory feedback from sleep-specific movements activates the brain. We prefer a third framework that encompasses the first two but also captures the diverse ways in which sleep modulates activity-dependent development throughout the nervous system. Appreciation of the third framework will spur progress toward a more comprehensive and cohesive understanding of both typical and atypical neurodevelopment.
Details
- Title: Subtitle
- Sleep, plasticity, and sensory neurodevelopment
- Creators
- Mark S Blumberg - University of IowaJames C DooleyAlexandre Tiriac
- Resource Type
- Journal article
- Publication Details
- Neuron, Vol.110(20), pp.3230-3242
- DOI
- 10.1016/j.neuron.2022.08.005
- PMID
- 36084653
- PMCID
- PMC9588561
- NLM abbreviation
- Neuron
- ISSN
- 0896-6273
- eISSN
- 1097-4199
- Grant note
- DOI: 10.13039/100009633, name: NICHD, award: R37-HD081168; DOI: 10.13039/100000002, name: National Institutes of Health
- Language
- English
- Date published
- 09/02/2022
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute; Biology
- Record Identifier
- 9984296993502771
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