SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research

Isaiah Norton; Ibn Essayed; Fan Zhang; Sonia Pujol; Alex Yarmarkovich; Alexandra Golby; Gordon Kindlmann; Demian Wassermann; Raul San José Estepar; Yogesh Rathi; Steve Pieper; Ron Kikinis; Hans Johnson; Carl-Fredrik Westin; Lauren O'Donnell

doi:10.1158/0008-5472.CAN-17-0332

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SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research

Journal article

Open access

Peer reviewed

SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research

Isaiah Norton, Ibn Essayed, Fan Zhang, Sonia Pujol, Alex Yarmarkovich, Alexandra Golby, Gordon Kindlmann, Demian Wassermann, Raul San José Estepar, Yogesh Rathi, …

Cancer research (Chicago, Ill.), Vol.77(21), pp.e101-e103

2017

DOI: 10.1158/0008-5472.CAN-17-0332

PMCID: PMC5679308

PMID: 29092950

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https://doi.org/10.1158/0008-5472.CAN-17-0332View

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Abstract

Diffusion magnetic resonance imaging (dMRI) is the only non-invasive method for mapping white matter connections in the brain. We describe SlicerDMRI, a software suite that enables visualization and analysis of dMRI for neuroscientific studies and patient-specific anatomical assessment. SlicerDMRI has been successfully applied in multiple studies of the human brain in health and disease, and here we especially focus on its cancer research applications. As an extension module of the 3D Slicer medical image computing platform, the SlicerDMRI suite enables dMRI analysis in a clinically relevant multimodal imaging workflow. Core SlicerDMRI functionality includes diffusion tensor estimation, white matter tractography with single and multi-fiber models, and dMRI quantification. SlicerDMRI supports clinical DICOM and research file formats, is open-source and cross-platform, and can be installed as an extension to 3D Slicer (www.slicer.org). More information, videos, tutorials, and sample data are available at dmri.slicer.org.

Physics

Biological Physics

Details

Title: Subtitle: SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research
Creators: Isaiah Norton - Brigham and Women's Hospital
Ibn Essayed - Brigham and Women's Hospital
Fan Zhang - Brigham and Women's Hospital
Sonia Pujol - Brigham and Women's Hospital
Alex Yarmarkovich - Isomics, Inc., Cambridge, Massachusetts.
Alexandra Golby - Brigham and Women's Hospital
Gordon Kindlmann - University of Chicago
Demian Wassermann - Institut national de recherche en sciences et technologies du numérique
Raul San José Estepar - Brigham and Women's Hospital
Yogesh Rathi - Brigham and Women's Hospital
Steve Pieper - Isomics, Inc., Cambridge, Massachusetts.
Ron Kikinis - Brigham and Women's Hospital
Hans Johnson - University of Iowa
Carl-Fredrik Westin - Brigham and Women's Hospital
Lauren O'Donnell - Brigham and Women's Hospital
Resource Type: Journal article
Publication Details: Cancer research (Chicago, Ill.), Vol.77(21), pp.e101-e103
DOI: 10.1158/0008-5472.CAN-17-0332
PMID: 29092950
PMCID: PMC5679308
NLM abbreviation: Cancer Res
ISSN: 0008-5472
eISSN: 1538-7445
Publisher: American Association for Cancer Research
Grant note: DOI: 10.13039/100000002, name: NIH NCI ITCR, award: U01CA199459; DOI: 10.13039/100000002, name: NIH, award: P41EB015898; DOI: 10.13039/100000002, name: NIH, award: P41EB015902; DOI: 10.13039/100000002, name: NIH, award: NIH R01MH074794, NIH R01MH097979, NIH U54EB005149
Language: English
Date published: 2017
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Electrical and Computer Engineering; Psychiatry
Record Identifier: 9984185364802771

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