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Solitary adult orbital myofibroma: Report of a case and review of the literature
Journal article   Open access   Peer reviewed

Solitary adult orbital myofibroma: Report of a case and review of the literature

Nicole C Morrow, Munir R Tanas, Nasreen A Syed and Anand Rajan KD
American journal of ophthalmology case reports, Vol.20, p.100955
12/2020
DOI: 10.1016/j.ajoc.2020.100955
PMID: 33089011
url
https://doi.org/10.1016/j.ajoc.2020.100955View
Published (Version of record) Open Access

Abstract

Myofibromas are benign soft tissue tumors commonly encountered in infancy and childhood. Developing usually within the first two years of life, they can be multicentric and involve deep visceral organs. We present the rare occurrence of a solitary orbital myofibroma in an adult patient. The clinical, histopathologic and immunohistochemical findings of the tumor are documented. A comprehensive review of pediatric and adult orbital and periocular involvement by myofibroma is presented. Its characteristic pathologic and molecular findings are reviewed. Myofibromas are uncommon but important tumors that can occur in the head and neck region, including the orbit. Seen more often in children, they can rarely be encountered in adult patients. Diagnosis is possible with a panel of immunostains and molecular analysis can be further confirmatory.
Myofibroma Myofibromatosis Myopericytoma PDGFRB mutation

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