Journal article
Somatostatin receptor imaging of non-small cell lung cancer with 99mTc depreotide
Seminars in nuclear medicine, Vol.32(2), pp.92-96
2002
DOI: 10.1053/snuc.2002.31564
PMID: 11965604
Abstract
Several tumors overexpress somatostatin receptors (SSTR) and can thus be imaged with radiolabeled analogues of somatostatin. Tc-99m depreotide is a new radiolabeled somatostatin analogue that shows high affinity for SSTR2, SSTR3, and SSTR5 subtypes. It has been recently FDA-approved for use in the evaluation of indeterminate solitary pulmonary nodules. SPECT with Tc-99m depreotide is highly accurate in this clinical setting and may be preferable to FDG-PET because of its lower cost and wider availability. Large studies are also underway to evaluate the accuracy of Tc-99m depreotide in staging of lung cancer.
Details
- Title: Subtitle
- Somatostatin receptor imaging of non-small cell lung cancer with 99mTc depreotide
- Creators
- Yusuf Menda - Division of Nuclear Medicine, University of Iowa College of Medicine Iowa City, IA, USADaniel Kahn - Division of Nuclear Medicine, University of Iowa College of Medicine Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Seminars in nuclear medicine, Vol.32(2), pp.92-96
- Publisher
- Elsevier Inc
- DOI
- 10.1053/snuc.2002.31564
- PMID
- 11965604
- ISSN
- 0001-2998
- eISSN
- 1558-4623
- Language
- English
- Date published
- 2002
- Academic Unit
- Radiology; Radiation Oncology
- Record Identifier
- 9984047895802771
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