Journal article
Sorting high-affinity aptamers in a single selection round
Nature chemical biology, Vol.21(7), pp.978-979
07/2025
DOI: 10.1038/s41589-025-01917-0
PMID: 40404900
Abstract
Aptamers are short, single-stranded DNA or RNA molecules that can bind target molecules with high specificity and affinity and have considerable potential as therapeutic agents and diagnostic tools. A new method, UltraSELEX, identifies optimal sequences from a single round of high-throughput screening.
Details
- Title: Subtitle
- Sorting high-affinity aptamers in a single selection round
- Creators
- Gayathri Kasirajan - University of IowaWilliam H Thiel - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Nature chemical biology, Vol.21(7), pp.978-979
- DOI
- 10.1038/s41589-025-01917-0
- PMID
- 40404900
- NLM abbreviation
- Nat Chem Biol
- ISSN
- 1552-4469
- eISSN
- 1552-4469
- Publisher
- NATURE PORTFOLIO
- Language
- English
- Electronic publication date
- 05/22/2025
- Date published
- 07/2025
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984824325402771
Metrics
5 Record Views