Journal article
Spatiotemporal Coupling of the Tongue in Amyotrophic Lateral Sclerosis
Journal of speech, language, and hearing research, Vol.55(6), pp.1897-1909
12/01/2012
DOI: 10.1044/1092-4388(2012/11-0259)
PMCID: PMC4607050
PMID: 22615476
Abstract
Purpose: The primary aim of the investigation was to identify deficits in spatiotemporal coupling between tongue regions in amyotrophic lateral sclerosis (ALS). The relations between disease-related changes in tongue movement patterns and speech intelligibility were also determined.
Methods: The authors recorded word productions from 11 individuals with ALS with mild, moderate, and severe dysarthria using an x-ray microbeam during word productions. A coupling index based on sliding window covariance was used to determine disease-related changes in the coupling between the tongue regions across each word.
Results: The results indicated decreased spatiotemporal coupling of mid-posterior tongue regions and reduced tongue speed in the ALS-moderate subgroup. Changes in the range of tongue coupling relations and speed of movement were highly correlated with speech intelligibility.
Conclusions: These results provide new insights into the loss of lingual motor control due to ALS and suggest that measures of tongue performance may provide useful indicators of bulbar disease severity and progression.
Details
- Title: Subtitle
- Spatiotemporal Coupling of the Tongue in Amyotrophic Lateral Sclerosis
- Creators
- Mili S. Kuruvilla - Nebraska Medical CenterJordan R. Green - University of Nebraska–LincolnYana Yunusova - University of TorontoKathy Hanford - University of Nebraska–Lincoln
- Resource Type
- Journal article
- Publication Details
- Journal of speech, language, and hearing research, Vol.55(6), pp.1897-1909
- Publisher
- Amer Speech-Language-Hearing Assoc
- DOI
- 10.1044/1092-4388(2012/11-0259)
- PMID
- 22615476
- PMCID
- PMC4607050
- ISSN
- 1092-4388
- eISSN
- 1558-9102
- Number of pages
- 13
- Grant note
- R01DC009890 / National Institute on Deafness and Other Communication Disorders; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Deafness & Other Communication Disorders (NIDCD) Bernice Ramsey Discovery Grant from ALS Canada
- Language
- English
- Date published
- 12/01/2012
- Academic Unit
- Communication Sciences and Disorders
- Record Identifier
- 9984446452502771
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