Journal article
Spatiotemporal movement variability in ALS: Speaking rate effects on tongue, lower lip, and jaw motor control
Journal of communication disorders, Vol.67, pp.22-34
05/01/2017
DOI: 10.1016/j.jcomdis.2017.05.002
PMCID: PMC5514846
PMID: 28528293
Abstract
Purpose: Although it is frequently presumed that bulbar muscle degeneration in Amyotrophic Lateral Sclerosis (ALS) is associated with progressive loss of speech motor control, empirical evidence is limited. Furthermore, because speaking rate slows with disease progression and rate manipulations are used to improve intelligibility in ALS, this study sought to (i) determine between and within-group differences in articulatory motor control as a result of speaking rate changes and (ii) identify the strength of association between articulatory motor control and speech impairment severity.
Method: Ten talkers with ALS and 11 healthy controls repeated the target sentence at habitual, fast, and slow rates. The spatiotemporal variability index (STI) was calculated to determine tongue, lower lip, and jaw movement variability.
Results: During habitual speech, talkers with mild-moderate dysarthria displayed significantly lower tongue and lip movement variability whereas those with severe dysarthria showed greater variability compared to controls. Within-group rate effects were significant only for talkers with ALS. Specifically, lip and tongue movement variability significantly increased during slow speech relative to habitual and fast speech. Finally, preliminary associations between speech impairment severity and movement variability were moderate to strong in talkers with ALS.
Conclusion: Between-group differences for habitual speech and within-group effects for slow speech replicated previous findings for lower lip and jaw movements. Preliminary findings of moderate to strong associations between speech impairment severity and STI suggest that articulatory variability may vary from pathologically low (possibly indicating articulatory compensation) to pathologically high variability (possibly indicating loss of control) with dysarthria progression in ALS.
Details
- Title: Subtitle
- Spatiotemporal movement variability in ALS: Speaking rate effects on tongue, lower lip, and jaw motor control
- Creators
- Mili Kuruvilla-Dugdale - University of MissouriAntje Mefferd - Vanderbilt University Medical Center
- Resource Type
- Journal article
- Publication Details
- Journal of communication disorders, Vol.67, pp.22-34
- DOI
- 10.1016/j.jcomdis.2017.05.002
- PMID
- 28528293
- PMCID
- PMC5514846
- NLM abbreviation
- J Commun Disord
- ISSN
- 0021-9924
- eISSN
- 1873-7994
- Publisher
- Elsevier
- Number of pages
- 13
- Grant note
- R03DC015075 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA R03DC015075 / NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Deafness & Other Communication Disorders (NIDCD)
- Language
- English
- Date published
- 05/01/2017
- Academic Unit
- Communication Sciences and Disorders
- Record Identifier
- 9984446065802771
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