Journal article
Spectral Doppler waveforms in systemic arteries and physiological significance of a patent ductus arteriosus
Journal of perinatology, Vol.31(3), pp.150-156
03/2011
DOI: 10.1038/jp.2010.83
PMID: 20651695
Abstract
Patent ductus arteriosus in extremely premature babies is associated with major neonatal morbidities, such as necrotizing enterocolitis and intraventricular hemorrhage. This may be attributable, at least in part, to systemic hypoperfusion secondary to ductal steal. A hemodynamically significant ductus arteriosus (HSDA) is known to be associated with altered systemic blood flow and end-organ hypoperfusion. Although descending aorta blood flow profiles may show abnormal diastolic retrograde flow, Doppler studies of blood flow in the systemic arteries may help improve our understanding of the relationship of a HSDA with these morbidities. In this article, we discuss aspects of diastolic blood flow reversal in the systemic arteries in premature infants with a hemodynamically significant duct. Whether these hemodynamic effects are significant enough to form the basis for initiating treatment is still unclear; these should form the basis for prospective studies.
Details
- Title: Subtitle
- Spectral Doppler waveforms in systemic arteries and physiological significance of a patent ductus arteriosus
- Creators
- A Sehgal - Monash Newborn, Monash Children's, Monash Medical Centre, Melbourne, VIC, Australia. Arvind.Sehgal@southernhealth.org.auP CoombsK TanP J McNamara
- Resource Type
- Journal article
- Publication Details
- Journal of perinatology, Vol.31(3), pp.150-156
- DOI
- 10.1038/jp.2010.83
- PMID
- 20651695
- NLM abbreviation
- J Perinatol
- ISSN
- 0743-8346
- eISSN
- 1476-5543
- Language
- English
- Date published
- 03/2011
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology; Internal Medicine
- Record Identifier
- 9984093493102771
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