Journal article
Spinal Nerve Sheath Tumors: Factors Associated with Postoperative Residual and Recurrent Tumors. A Single-Center Experience
World neurosurgery, Vol.167, pp.e1062-e1071
09/09/2022
DOI: 10.1016/j.wneu.2022.08.151
Abstract
Background
Spinal schwannomas (SSs) are usually benign tumors with a good prognosis when treated by surgical excision. However, complete resection can be complicated by factors such as the tumor location and configuration. In the present study, we sought to identify the factors associated with incomplete surgical resection (residual) and the factors associated with tumor recurrence.
Methods
We performed a retrospective review of 113 cases of SSs treated surgically from 2008 to 2021.
Results
Of the 113 SSs, 102 were benign and 2 were malignant nerve sheath tumors. Of the 102 benign SSs, gross total resection (GTR) was performed for 87, with 8 displaying residual and 7, recurrent tumor. We found a significantly higher ratio of cervical and sacral tumors (P = 0.008 and P = 0.004, respectively), dumbbell and foraminal configurations (P < 0.0001 and P = 0.0006, respectively), and larger tumor volumes (P = 0.003) in the residual and recurrent cohorts compared with the GTR cohort. A second operation was performed for 2 patients in the residual and 4 patients in the recurrent cohorts. The total complication rate was 6%.
Conclusions
We found that most benign SSs will be amenable to GTR (85% of cases), with an excellent prognosis. The patients with residual or recurrent tumor were more likely to have had a cervical or sacral location, a dumbbell or foraminal configuration, and a larger tumor volume. Except for 1 new SS and 1 recurrent tumor that had necessitated a lateral approach, the remainder had been treated using a posterior approach. At surgery, ultrasonography of the canal is advisable to ensure that the intra- and extraspinal components of dumbbell lesions have both been entirely removed.
Details
- Title: Subtitle
- Spinal Nerve Sheath Tumors: Factors Associated with Postoperative Residual and Recurrent Tumors. A Single-Center Experience
- Creators
- Brian J Park - University of IowaJennifer NoellerColin GoldKirill V NourskiGirish BathlaPatrick W Hitchon
- Resource Type
- Journal article
- Publication Details
- World neurosurgery, Vol.167, pp.e1062-e1071
- DOI
- 10.1016/j.wneu.2022.08.151
- ISSN
- 1878-8750
- eISSN
- 1878-8769
- Language
- English
- Date published
- 09/09/2022
- Academic Unit
- Radiology; Iowa Neuroscience Institute; Roy J. Carver Department of Biomedical Engineering; Neurosurgery
- Record Identifier
- 9984303910302771
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