Sporminarins A and B: antifungal metabolites from a fungicolous isolate of Sporormiella minimoides

Sanjay V Mudur; James B Gloer; Donald T Wicklow

doi:10.1038/ja.2006.70

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Sporminarins A and B: antifungal metabolites from a fungicolous isolate of Sporormiella minimoides

Journal article

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Sporminarins A and B: antifungal metabolites from a fungicolous isolate of Sporormiella minimoides

Sanjay V Mudur, James B Gloer and Donald T Wicklow

Journal of antibiotics, Vol.59(8), pp.500-506

08/2006

DOI: 10.1038/ja.2006.70

PMID: 17080687

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Abstract

Cultures of a fungicolous isolate of Sporormiella minimoides afforded two new polyketide metabolites which we have named sporminarins A (1) and B (2). The planar structures of 1 and 2 were elucidated by analysis of NMR and MS data, and by chemical methods. 1 exhibited significant antifungal activity against Aspergillus flavus.

Alkenes - pharmacology

Antifungal Agents - chemistry

Antifungal Agents - isolation & purification

Antifungal Agents - pharmacology

Ascomycota

Aspergillus flavus - drug effects

Inhibitory Concentration 50

Mass Spectrometry

Microbial Sensitivity Tests

Nuclear Magnetic Resonance, Biomolecular

Pyrans - pharmacology

Details

Title: Subtitle: Sporminarins A and B: antifungal metabolites from a fungicolous isolate of Sporormiella minimoides
Creators: Sanjay V Mudur - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA
James B Gloer
Donald T Wicklow
Resource Type: Journal article
Publication Details: Journal of antibiotics, Vol.59(8), pp.500-506
DOI: 10.1038/ja.2006.70
PMID: 17080687
NLM abbreviation: J Antibiot (Tokyo)
ISSN: 0021-8820
eISSN: 1881-1469
Grant note: GM 60600 / NIGMS NIH HHS
Language: English
Date published: 08/2006
Academic Unit: Chemistry
Record Identifier: 9984216715702771

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