Journal article
Spot-welding solid targets for high current cyclotron irradiation
Applied radiation and isotopes, Vol.118, pp.350-353
12/01/2016
DOI: 10.1016/j.apradiso.2016.10.010
PMCID: PMC5164840
PMID: 27771445
Abstract
Zirconium-89 finds broad application for use in positron emission tomography. Its cyclotron production has been limited by the heat transfer from yttrium targets at high beam currents. A spot welding technique allows a three-fold increase in beam current, without affecting Zr-89 quality. An yttrium foil, welded to a jet-cooled tantalum support base accommodates a 50 A proton beam degraded to 14 MeV. The resulting activity yield of 48 4 MBq/(mu A.hr) now extends the outreach of Zr-89 for a broader distribution.
Details
- Title: Subtitle
- Spot-welding solid targets for high current cyclotron irradiation
- Creators
- Paul A. Ellison - University of Wisconsin–MadisonHector F. Valdovinos - University of Wisconsin–MadisonStephen A. Graves - Univ Wisconsin, Dept Med Phys, Sch Med & Publ Hlth, 1111 Highland Ave, Madison, WI 53705 USATodd E. Barnhart - University of Wisconsin–MadisonRobert J. Nickles - University of Wisconsin–Madison
- Resource Type
- Journal article
- Publication Details
- Applied radiation and isotopes, Vol.118, pp.350-353
- Publisher
- Elsevier
- DOI
- 10.1016/j.apradiso.2016.10.010
- PMID
- 27771445
- PMCID
- PMC5164840
- ISSN
- 0969-8043
- eISSN
- 1872-9800
- Number of pages
- 4
- Grant note
- T32CA009206 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) Michael Phelps Family Foundation T32-CA009206 / NIH Radiological Sciences Training Grant
- Language
- English
- Date published
- 12/01/2016
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Radiation Oncology
- Record Identifier
- 9984383925702771
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