Journal article
Stability of Sublines in the R3327-H Rat Prostatic Tumor
The Journal of urology, Vol.136(6), pp.1335-1342
12/1986
DOI: 10.1016/S0022-5347(17)45333-X
PMID: 3773119
Abstract
Over several years of in vivo maintenance passage the R3327-H rat prostatic tumor has given rise to nine unique sublines in our laboratory. Some have emerged under selective treatment pressure while others apparently represent spontaneous or random modulation. Each new subline embodied an altered histology, growth rate, metastatic pattern or treatment sensitivity in comparison to its parent subline. However, each has been subsequently passaged enough times to provide evidence of considerable phenotypic stability, a notable point in view of the R3327 tumor's well known potential for modulation.
Details
- Title: Subtitle
- Stability of Sublines in the R3327-H Rat Prostatic Tumor
- Creators
- William W Bonney - From the Departments of Urology, Pathology and Preventive Medicine, Veterans Administration Medical Center and University of Iowa Hospitals, Iowa City, IowaJohn Johnson - From the Departments of Urology, Pathology and Preventive Medicine, Veterans Administration Medical Center and University of Iowa Hospitals, Iowa City, IowaRobert A Robinson - From the Departments of Urology, Pathology and Preventive Medicine, Veterans Administration Medical Center and University of Iowa Hospitals, Iowa City, IowaPeter A Lachenbruch - From the Departments of Urology, Pathology and Preventive Medicine, Veterans Administration Medical Center and University of Iowa Hospitals, Iowa City, IowaRonald Leafgreen - From the Departments of Urology, Pathology and Preventive Medicine, Veterans Administration Medical Center and University of Iowa Hospitals, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- The Journal of urology, Vol.136(6), pp.1335-1342
- DOI
- 10.1016/S0022-5347(17)45333-X
- PMID
- 3773119
- ISSN
- 0022-5347
- eISSN
- 1527-3792
- Language
- English
- Date published
- 12/1986
- Academic Unit
- Oral Pathology, Radiology and Medicine; Pathology; Urology
- Record Identifier
- 9984047614002771
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