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Stability of streptococcal pyrogenic exotoxin production with laboratory manipulation of group A streptococci
Journal article   Peer reviewed

Stability of streptococcal pyrogenic exotoxin production with laboratory manipulation of group A streptococci

Edward L Kaplan, Dwight R Johnson, Anthony Wlazlo, Michael H Kim and Patrick M Schlievert
The Journal of infectious diseases, Vol.164(6), pp.1210-1211
12/1991
DOI: 10.1093/infdis/164.6.1210
PMID: 1955721

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Abstract

Because of reported differences in the production of streptococcal pyrogenic exotoxins by group A strains associated with severe streptococcal infections, the stability of exotoxin production by specific strains was examined by passing group A streptococci on blood agar culture plates daily for 20 days. No changes were detected in either exotoxin genes or in exotoxin production during this time, suggesting that these reported differences are due to other explanations such as differences in the strains collected from various geographic areas or to laboratory methodologic differences.
Membrane Proteins Streptococcus pyogenes - genetics Exotoxins - biosynthesis Pyrogens - biosynthesis Humans Exotoxins - genetics Streptococcus pyogenes - metabolism Pyrogens - genetics Bacterial Proteins

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