Journal article
Staged Approaches to Restorative Proctocolectomy with Ileoanal Pouch-When and Why?
Journal of laparoendoscopic & advanced surgical techniques. Part A, Vol.31(8), pp.875-880
08/01/2021
DOI: 10.1089/lap.2021.0060
PMID: 34182807
Abstract
Restorative proctocolectomy (RPC) with ileal pouch anal-anastomosis (IPAA) is commonly performed for patients with ulcerative colitis, familial adenomatous polyposis, and selected phenotypes of Crohn's disease (CD). Due to concerns about the effects of surgical complications on pouch functional outcomes, debate remains surrounding when and whether RPC with IPAA should be performed in a staged manner. Particularly debated are the timings of the IPAA, whether it is constructed at time of the proctocolectomy and whether to utilize temporary fecal diversion with a loop ileostomy. RPC with IPAA can be performed in one, two, or three stages, with each stage typically separated by 3-6 months. Proponents of a staged approach argue that poor pouch function, which is often a result of IPAA complications, including leak and infection, can be difficult to overcome and mandate additional, major surgeries, and that staging pouch creation and pairing with a protective ileostomy reduce those complications. However, subjecting patients to multiple surgeries and prolonging their time with an ileostomy present unique risks as well. Surgeons' experience and preference and patient characteristics need to be considered when determining operative planning. Highly selected patients with CD can be considered for RPC with IPAA, although with an acknowledgment of inherently higher pouch failure rates. Understanding the short- and long-term consequences of RPC with IPAA construction can help surgeons determine the appropriate approach.
Details
- Title: Subtitle
- Staged Approaches to Restorative Proctocolectomy with Ileoanal Pouch-When and Why?
- Creators
- Dakota T. Thompson - University of Iowa Hospitals and ClinicsJennifer E. Hrabe - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Journal of laparoendoscopic & advanced surgical techniques. Part A, Vol.31(8), pp.875-880
- Publisher
- Mary Ann Liebert, Inc
- DOI
- 10.1089/lap.2021.0060
- PMID
- 34182807
- ISSN
- 1092-6429
- eISSN
- 1557-9034
- Number of pages
- 6
- Grant note
- T32CA148062 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Language
- English
- Date published
- 08/01/2021
- Academic Unit
- Surgery
- Record Identifier
- 9984544602102771
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