Journal article
Standard Operating Procedures for Biospecimen Collection, Processing, and Storage: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer
Pancreas, Vol.47(10), pp.1213-1221
11/2018
DOI: 10.1097/MPA.0000000000001171
PMCID: PMC6197069
PMID: 30325860
Abstract
High-quality and well-annotated biorepositories are needed to better understand the pathophysiology and biologic mechanisms of chronic pancreatitis (CP) and its consequences. We report a methodology for the development of a robust standard operating procedure (SOP) for a biorepository based on the experience of the clinical centers within the consortium to study Chronic Pancreatitis, Diabetes and Pancreas Cancer Clinical Centers (CPDPC), supported by the National Cancer Institute and the National Institute for Diabetes and Digestive and Kidney Diseases as a unique multidisciplinary model to study CP, diabetes, and pancreatic cancer in both children and adults. Standard operating procedures from the CPDPC centers were evaluated and consolidated. The literature was reviewed for standard biorepository operating procedures that facilitated downstream molecular analysis. The existing literature on biobanking practices was harmonized with the SOPs from the clinical centers to produce a biorepository for pancreatic research. This article reports the methods and basic principles behind the creation of SOPs to develop a biorepository for the CPDPC. These will serve as a guide for investigators developing biorepositories in pancreas research. Rigorous and meticulous adherence to standardized biospecimen collection will facilitate investigations to better understand the pathophysiology and biologic mechanisms of CP, diabetes, and pancreatic cancer.
Details
- Title: Subtitle
- Standard Operating Procedures for Biospecimen Collection, Processing, and Storage: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer
- Creators
- William E FisherZobeida Cruz-Monserrate - Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, and Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OHAmy L McElhanyGregory B Lesinski - Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University, Atlanta, GAPhil A Hart - Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, and Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OHRia Ghosh - Department of Biostatistics, The University of Texas MD Anderson Cancer CenterGeorge Van BurenDouglas S Fishman - Department of Pediatrics, Baylor College of Medicine, Houston, TXJo Ann S Rinaudo - Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, RockvilleJose Serrano - Division of Digestive Diseases and Nutrition, National Institutes of Diabetes and Digestive and Kidney Diseases, Bethesda, MDSudhir Srivastava - Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, RockvilleThomas Mace - Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, and Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OHMark Topazian - Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MNZiding Feng - Department of Biostatistics, The University of Texas MD Anderson Cancer CenterDhiraj Yadav - Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, Pittsburgh, PAStephen J Pandol - Division of Digestive and Liver Diseases, Cedars-Sinai Medical Center, Los Angeles, CASteven J Hughes - Department of Surgery, University of Florida College of Medicine, Gainesville, FLRobert Y Liu - Clinical Research Support Center, The University of Texas MD Anderson Cancer Center, Houston, TXEmily Lu - Clinical Research Support Center, The University of Texas MD Anderson Cancer Center, Houston, TXRobert Orr - Indiana Clinical and Translational Sciences Institute, Specimen Storage Facility, Indianapolis, INDavid C Whitcomb - Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MNAmer S Abouhamze - Clinical and Translational Sciences, University of Florida, Gainesville, FLHanno Steen - Departments of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MAZachary M Sellers - Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Lucile Packard Children's Hospital and Stanford University School of Medicine, Stanford, CADavid M Troendle - Department of Pediatrics, University of Texas Southwestern Medical School, Dallas, TXAliye Uc - Stead Family Department of Pediatrics, University of Iowa, Stead Family Children's Hospital, Iowa City, IAMark E Lowe - Department of Pediatrics, Washington University School of Medicine, St Louis, MODarwin L Conwell - Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, and Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH
- Resource Type
- Journal article
- Publication Details
- Pancreas, Vol.47(10), pp.1213-1221
- DOI
- 10.1097/MPA.0000000000001171
- PMID
- 30325860
- PMCID
- PMC6197069
- NLM abbreviation
- Pancreas
- ISSN
- 0885-3177
- eISSN
- 1536-4828
- Publisher
- United States
- Grant note
- P50 AA011999 / NIAAA NIH HHS U01 DK108306 / NIDDK NIH HHS U01 DK108326 / NIDDK NIH HHS U01 DK108334 / NIDDK NIH HHS U01 DK108314 / NIDDK NIH HHS P01 DK098108 / NIDDK NIH HHS U01 DK108327 / NIDDK NIH HHS P30 DK054759 / NIDDK NIH HHS U01 DK108320 / NIDDK NIH HHS
- Language
- English
- Date published
- 11/2018
- Academic Unit
- Stead Family Department of Pediatrics; Radiation Oncology; Gastroenterology, Hepatology, Pancreatology, and Nutrition
- Record Identifier
- 9984046820302771
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