Journal article
Staphylococcus aureus Community-Acquired Pneumonia During the 2006 to 2007 Influenza Season
Annals of emergency medicine, Vol.53(3), pp.358-365
2009
DOI: 10.1016/j.annemergmed.2008.04.027
PMID: 18534715
Abstract
Staphylococcus aureus is a cause of community-acquired pneumonia that can follow influenza infection. In response to a number of cases reported to public health authorities in early 2007, additional case reports were solicited nationwide to better define
S aureus community-acquired pneumonia during the 2006 to 2007 influenza season.
Cases were defined as primary community-acquired pneumonia caused by
S aureus occurring between November 1, 2006, and April 30, 2007. Case finding was conducted through an Emerging Infections Network survey and through contacts with state and local health departments.
Overall, 51 cases were reported from 19 states; 37 (79%) of 47 with known susceptibilities involved infection with methicillin-resistant
S aureus (MRSA). The median age of case patients was 16 years, and 44% had no known pertinent medical history. Twenty-two (47%) of 47 case patients with information about other illnesses were diagnosed with a concurrent or antecedent viral infection during their illness, and 11 of 33 (33%) who were tested had laboratory-confirmed influenza. Of the 37 patients with MRSA infection, 16 (43%) were empirically treated with antimicrobial agents recommended for MRSA community-acquired pneumonia. Twenty-four (51%) of 47 patients for whom final disposition was known died a median of 4 days after symptom onset.
S aureus continues to cause community-acquired pneumonia, with most reported cases caused by MRSA and many occurring with or after influenza. In this series, patients were often otherwise healthy young people and mortality rates were high. Further prospective investigation is warranted to clarify infection incidence, risk factors, and preventive measures.
Details
- Title: Subtitle
- Staphylococcus aureus Community-Acquired Pneumonia During the 2006 to 2007 Influenza Season
- Creators
- Alexander J Kallen - Division of Healthcare Quality Promotion, National Center for Preparedness, Detection and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GAJoan Brunkard - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GAZachary Moore - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GAPhilip Budge - Division of Healthcare Quality Promotion, National Center for Preparedness, Detection and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GAKathryn E Arnold - Georgia Department of Health, Atlanta, GAGregory Fosheim - Division of Healthcare Quality Promotion, National Center for Preparedness, Detection and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GALyn Finelli - Office of Workforce and Career Development, and Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GASusan E Beekmann - Infectious Diseases Society of America Emerging Infections Network, Iowa City, IAPhilip M Polgreen - Infectious Diseases Society of America Emerging Infections Network, Iowa City, IARachel Gorwitz - Division of Healthcare Quality Promotion, National Center for Preparedness, Detection and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GAJeffrey Hageman - Division of Healthcare Quality Promotion, National Center for Preparedness, Detection and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA
- Resource Type
- Journal article
- Publication Details
- Annals of emergency medicine, Vol.53(3), pp.358-365
- DOI
- 10.1016/j.annemergmed.2008.04.027
- PMID
- 18534715
- NLM abbreviation
- Ann Emerg Med
- ISSN
- 0196-0644
- eISSN
- 1097-6760
- Publisher
- Mosby, Inc
- Language
- English
- Date published
- 2009
- Academic Unit
- Infectious Diseases; Epidemiology; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984094346302771
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