Staphylococcus aureus nasal colonization and colonization or infection at other body sites in patients on a burn trauma unit

Amber Reighard; Daniel Diekema; Lucy Wibbenmeyer; Melissa Ward; Loreen Herwaldt

doi:10.1086/598681

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Staphylococcus aureus nasal colonization and colonization or infection at other body sites in patients on a burn trauma unit

Journal article

Peer reviewed

Staphylococcus aureus nasal colonization and colonization or infection at other body sites in patients on a burn trauma unit

Amber Reighard, Daniel Diekema, Lucy Wibbenmeyer, Melissa Ward and Loreen Herwaldt

Infection control and hospital epidemiology, Vol.30(8), pp.721-726

08/2009

DOI: 10.1086/598681

PMID: 19580438

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Abstract

To determine whether Staphylococcus aureus isolates from the nares of patients on a burn trauma unit were related to isolates colonizing or infecting other body sites. Active surveillance for S. aureus, a case-control study, and pulsed-field gel electrophoresis of S. aureus isolates. A burn trauma unit of a Midwestern university teaching hospital. Patients admitted from February 1, 2002, through March 30, 2007, who had S. aureus isolated either from a nasal culture and from another body site (case patients) or from a nasal culture alone (control subjects). Nineteen patients met the case patient definition and had paired isolates from the nares and an additional site available for typing. Of the 19 case patients, 8 had infections, 7 of which were caused by methicillin-resistant S. aureus (5 USA100 strain and 2 USA300 strain). A total length of stay of more than 3 weeks (odds ratio [OR], 8.75 [95% confidence interval {CI}, 2.2-34.6]; P = .002), residence in a long-term care facility (OR, 9.4 [95% CI, 2.1-42.5]; P = .004), and diabetes (OR, 3.2 [95% CI, 1.0-10.0]; P = .05) were associated with the isolation of S. aureus from the nares and other sites. Seventeen case patients (89.5%) had closely related isolates obtained from culture of samples from the nares and from other sites. Prolonged length of stay, diabetes, or residing in a long-term care facility increased the risk of having S. aureus at sites other than the nares. S. aureus isolates from other body sites usually were closely related to nasal isolates. Most case patients had colonized or infected wounds that could be a source of S. aureus for other patients.

Carrier State - epidemiology

Humans

Middle Aged

Carrier State - microbiology

Male

Long-Term Care

Case-Control Studies

Young Adult

Bacterial Typing Techniques

Adult

Female

Staphylococcal Infections - microbiology

Odds Ratio

Cross Infection - epidemiology

Length of Stay

Staphylococcus aureus - isolation & purification

Burns - microbiology

Burn Units - statistics & numerical data

Diabetes Mellitus

Wound Infection - epidemiology

Staphylococcal Infections - epidemiology

Cross Infection - microbiology

Wound Infection - microbiology

Nasal Cavity - microbiology

Methicillin-Resistant Staphylococcus aureus - isolation & purification

Details

Title: Subtitle: Staphylococcus aureus nasal colonization and colonization or infection at other body sites in patients on a burn trauma unit
Creators: Amber Reighard - Departments of Internal Medicine, University of Iowa, Iowa City, USA
Daniel Diekema
Lucy Wibbenmeyer
Melissa Ward
Loreen Herwaldt
Resource Type: Journal article
Publication Details: Infection control and hospital epidemiology, Vol.30(8), pp.721-726
DOI: 10.1086/598681
PMID: 19580438
NLM abbreviation: Infect Control Hosp Epidemiol
ISSN: 0899-823X
eISSN: 1559-6834
Publisher: United States
Language: English
Date published: 08/2009
Academic Unit: Infectious Diseases; Epidemiology; Pathology; Surgery; Injury Prevention Research Center; Internal Medicine
Record Identifier: 9983986370302771

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