Journal article
Stargardt disease masquerades
Current opinion in ophthalmology, Vol.32(3), pp.214-224
05/01/2021
DOI: 10.1097/ICU.0000000000000750
PMID: 33653979
Abstract
Stargardt disease is the most common inherited macular dystrophy but has a wide clinical spectrum, and several inherited macular dystrophies have phenotypic similarities that can make clinical diagnosis challenging. This review seeks to highlight key clinical and multimodal imaging features to aid clinicians in accurate diagnosis.
Multimodal imaging has provided additional information to aid in the diagnosis of Stargardt disease and its masquerades. These data from multimodal imaging are important to correlate with findings from clinical examination to help support the clinical diagnosis or guide molecular investigations.
This review highlights the key similarities and differences, in history, clinical examination and multimodal imaging, to help distinguish between Stargardt disease and other macular dystrophies. These findings can help direct a focused molecular analysis for accurate diagnosis, which is critical in the era of gene and stem cell therapies.
Details
- Title: Subtitle
- Stargardt disease masquerades
- Creators
- Aaron M Ricca - Institute for Vision Research, Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USAIan C HanElliott H Sohn
- Resource Type
- Journal article
- Publication Details
- Current opinion in ophthalmology, Vol.32(3), pp.214-224
- DOI
- 10.1097/ICU.0000000000000750
- PMID
- 33653979
- ISSN
- 1040-8738
- eISSN
- 1531-7021
- Language
- English
- Date published
- 05/01/2021
- Academic Unit
- Fraternal Order of Eagles Diabetes Research Center; Ophthalmology and Visual Sciences
- Record Identifier
- 9984101614402771
Metrics
21 Record Views