Journal article
Statin use does not prevent recurrent adenomatous polyp formation in a VA population
Indian journal of gastroenterology, Vol.29(3), pp.106-111
05/2010
DOI: 10.1007/s12664-010-0032-1
PMID: 20658327
Abstract
To evaluate whether statin use was associated with recurrent adenomatous polyps.We conducted a retrospective cohort study. We used electronic health records to evaluate veterans who underwent polypectomy between January 1, 1999 and December 31, 2001 and surveillance colonoscopy by December 2006. We obtained data on pathology, demographics, body mass index, comorbidity, habits, family history, and medications. We used multivariate proportional hazards regression models to analyze data.We evaluated 197 eligible patients from among 821 who underwent colonoscopy during this period; their mean (SD) age was 63.1 (8.8) years, 192 (98%) were men, and 80 (41%) non-Hispanic white. Surveillance colonoscopy was performed after a mean (SD) 1207 (452) days and 108 (55%) patients had recurrent adenomas. During follow-up, 88 (47%) of patients received statins, but use was not protective against recurrent adenomas (hazard ratio = 1.36, 95% CI 0.35–8.27). Only number of polyps at initial colonoscopy predicted recurrent adenomas (1.98, 95% CI 1.27–3.08).The use of statins was not protective against the recurrence of adenomatous polyps.
Details
- Title: Subtitle
- Statin use does not prevent recurrent adenomatous polyp formation in a VA population
- Creators
- Nikki Parker-Ray - Southwest Gastroenterology Albuquerque NM USAJehad Barakat - New Mexico VA Health Care System Mailstop 111, 1501 San Pedro Drive SE Albuquerque NM 87108 USAPraveen Roy - Albuquerque Health Partners Albuquerque NM USARobert White - Lovelace Clinic Foundation Albuquerque NM USARonald Schrader - University of New Mexico School of Medicine Albuquerque NM USARichard Hoffman - New Mexico VA Health Care System Mailstop 111, 1501 San Pedro Drive SE Albuquerque NM 87108 USA
- Resource Type
- Journal article
- Publication Details
- Indian journal of gastroenterology, Vol.29(3), pp.106-111
- Publisher
- Springer-Verlag
- DOI
- 10.1007/s12664-010-0032-1
- PMID
- 20658327
- ISSN
- 0254-8860
- eISSN
- 0975-0711
- Language
- English
- Date published
- 05/2010
- Academic Unit
- Epidemiology; General Internal Medicine; Internal Medicine
- Record Identifier
- 9984094584402771
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