Journal article
Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases 2017 An Official American Thoracic Society Workshop Report
American journal of respiratory cell and molecular biology, Vol.61(4), pp.429-439
10/01/2019
DOI: 10.1165/rcmb.2019-0286ST
PMCID: PMC6775946
PMID: 31573338
Abstract
The University of Vermont Larner College of Medicine, in collaboration with the National Heart, Lung, and Blood Institute (NHLBI), the Alpha-1 Foundation, the American Thoracic Society, the Cystic Fibrosis Foundation, the European Respiratory Society, the International Society for Cell & Gene Therapy, and the Pulmonary Fibrosis Foundation, convened a workshop titled "Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases" from July 24 through 27, 2017, at the University of Vermont, Burlington, Vermont. The conference objectives were to review and discuss current understanding of the following topics: 1) stem and progenitor cell biology and the role that they play in endogenous repair or as cell therapies after lung injury, 2) the emerging role of extracellular vesicles as potential therapies, 3) ex vivo bioengineering of lung and airway tissue, and 4) progress in induced pluripotent stem cell protocols for deriving lung cell types and applications in disease modeling. All of these topics are research areas in which significant and exciting progress has been made over the past few years. In addition, issues surrounding the ethics and regulation of cell therapies worldwide were discussed, with a special emphasis on combating the growing problem of unproven cell interventions being administered to patients with lung diseases. Finally, future research directions were discussed, and opportunities for both basic and translational research were identified.
Details
- Title: Subtitle
- Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases 2017 An Official American Thoracic Society Workshop Report
- Creators
- Amy L. Ryan - University of Southern CaliforniaLaertis Ikonomou - Boston UniversitySadaf Atarod - Boston UniversityDeniz A. Bolukbas - BioengineeringJennifer Collins - Erasmus Univ, Med Ctr, Sophia Childrens Hosp, Dept Paediat Surg, Rotterdam, NetherlandsRob Freishtat - George Washington UniversityFinn Hawkins - Boston UniversitySarah E. Gilpin - Massachusetts General HospitalFranziska E. Uhl - Lund UniversityJuan Jose Uriarte - Lund UniversityDaniel J. Weiss - University of VermontDarcy E. Wagner - Lund UniversityAmerican Thoracic Society Assembly on Respiratory Cell and Molecular Biology Stem Cell Working Group Subcommittee
- Resource Type
- Journal article
- Publication Details
- American journal of respiratory cell and molecular biology, Vol.61(4), pp.429-439
- Publisher
- Amer Thoracic Soc
- DOI
- 10.1165/rcmb.2019-0286ST
- PMID
- 31573338
- PMCID
- PMC6775946
- ISSN
- 1044-1549
- eISSN
- 1535-4989
- Number of pages
- 11
- Grant note
- European Respiratory Society R13HL139002 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) Alpha-1 Foundation National Heart, Lung, and Blood Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) John W. Walsh Memorial Travel Scholarship
- Language
- English
- Date published
- 10/01/2019
- Academic Unit
- Anatomy and Cell Biology
- Record Identifier
- 9984284346802771
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