Journal article
Stem cells, cell therapies, and bioengineering in lung biology and disease 2021
American journal of physiology. Lung cellular and molecular physiology, Vol.323(3), pp.L341-L354
09/01/2022
DOI: 10.1152/ajplung.00113.2022
PMCID: PMC9484991
PMID: 35762622
Abstract
The 9th biennial conference titled "Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases" was hosted virtually, due to the ongoing COVID-19 pandemic, in collaboration with the University of Vermont Larner College of Medicine, the National Heart, Lung, and Blood Institute, the Alpha-1 Foundation, the Cystic Fibrosis Foundation, and the International Society for Cell & Gene Therapy. The event was held from July 12th through 15th, 2021 with a pre-conference workshop held on July 9th. As in previous years, the objectives remained to review and discuss the status of active research areas involving stem cells (SCs), cellular therapeutics, and bioengineering as they relate to the human lung. Topics included 1) technological advancements in the in situ analysis of lung tissues, 2) new insights into stem cell signaling and plasticity in lung remodeling and regeneration, 3) the impact of extracellular matrix in stem cell regulation and airway engineering in lung regeneration, 4) differentiating and delivering stem cell therapeutics to the lung, 5) regeneration in response to viral infection, and 6) ethical development of cell-based treatments for lung diseases. This selection of topics represents some of the most dynamic and current research areas in lung biology. The virtual workshop included active discussion on state-of-the-art methods relating to the core features of the 2021 conference, including in situ proteomics, lung-on-chip, induced pluripotent stem cell (iPSC)-airway differentiation, and light sheet microscopy. The conference concluded with an open discussion to suggest funding priorities and recommendations for future research directions in basic and translational lung biology.
Details
- Title: Subtitle
- Stem cells, cell therapies, and bioengineering in lung biology and disease 2021
- Creators
- Laertis Ikonomou - Boston UniversityMattias Magnusson - Lund UniversityRuben Dries - Boston UniversityErica L. Herzog - Yale School of MedicineRobert E. Hynds - University College LondonZea Borok - University of California, San DiegoJin-Ah Park - Harvard UniversitySteven Skolasinski - University of MinnesotaJanette K. Burgess - University Medical Center GroningenLeigh Turner - University of California, IrvineSarah M. Mojarad - University of Southern CaliforniaJohn E. Mahoney - Cystic Fibrosis FoundationThomas Lynch - University of Iowa, Cardiothoracic SurgeryMareike Lehmann - Helmholtz Zentrum MünchenVictor J. Thannickal - Tulane Univ, Sch Med, John W Deming Dept Med, 1430 Tulane Ave, New Orleans, LA 70112 USAJamie L. Hook - Icahn School of Medicine at Mount SinaiAndrew E. Vaughan - University of PennsylvaniaEvan T. Hoffman - University of VermontDaniel J. Weiss - University of VermontAmy L. Ryan - University of Iowa, Anatomy and Cell Biology
- Resource Type
- Journal article
- Publication Details
- American journal of physiology. Lung cellular and molecular physiology, Vol.323(3), pp.L341-L354
- Publisher
- Amer Physiological Soc
- DOI
- 10.1152/ajplung.00113.2022
- PMID
- 35762622
- PMCID
- PMC9484991
- ISSN
- 1040-0605
- eISSN
- 1522-1504
- Number of pages
- 14
- Grant note
- R13HL149436; R13HL160043-01 / National Heart, Lung, and Blood Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI)
- Language
- English
- Date published
- 09/01/2022
- Academic Unit
- Anatomy and Cell Biology; Cardiothoracic Surgery
- Record Identifier
- 9984460056302771
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