Stem cells in airway smooth muscle: state of the art

Jaime Murphy; Ross Summer; Alan Fine

doi:10.1513/pats.200704-052VS

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Stem cells in airway smooth muscle: state of the art

Journal article

Open access

Stem cells in airway smooth muscle: state of the art

Jaime Murphy, Ross Summer and Alan Fine

Proceedings of the American Thoracic Society, Vol.5(1), pp.11-14

01/01/2008

DOI: 10.1513/pats.200704-052VS

PMCID: PMC2645296

PMID: 18094079

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https://europepmc.org/articles/pmc2645296View

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Abstract

Very little is known regarding the function, origin, and turnover of airway smooth muscle (ASM). In this article, we discuss the embryological development of ASM, and provide information regarding candidate mesenchymal ASM progenitor cell populations specifically in relation to airway remodeling. This review also highlights the current limitations in studying ASM biology, and underscores the need for novel molecular tools and markers that will refine our understanding of this cell type in lung homeostasis and disease.

Animals

Cell Differentiation - physiology

Humans

Muscle, Smooth - cytology

Muscle, Smooth - embryology

Respiratory System - embryology

Stem Cells - physiology

Details

Title: Subtitle: Stem cells in airway smooth muscle: state of the art
Creators: Jaime Murphy - Boston University
Ross Summer - Boston University
Alan Fine - Boston University
Resource Type: Journal article
Publication Details: Proceedings of the American Thoracic Society, Vol.5(1), pp.11-14
Publisher: American Thoracic Society
DOI: 10.1513/pats.200704-052VS
PMID: 18094079
PMCID: PMC2645296
ISSN: 1546-3222
eISSN: 1943-5665
Grant note: R21 HL08277 / NHLBI NIH HHS K08 HL077138 / NHLBI NIH HHS
Language: English
Date published: 01/01/2008
Academic Unit: Internal Medicine
Record Identifier: 9984694744202771

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