Journal article
Stenting in Intracranial Stenosis: Current Controversies and Future Directions
Current atherosclerosis reports, Vol.17(8), pp.1-9
08/2015
DOI: 10.1007/s11883-015-0527-4
PMID: 26104430
Abstract
Angioplasty and stenting for intracranial atherosclerotic stenosis (ICAS) are a last resort for patients with high-grade intracranial stenosis with multiple ischemic events unresponsive to medical therapy. Medical management, consisting of aggressive risk factor control and dual antiplatelet therapy, is superior to angioplasty and stenting for the prevention of future stroke. Future studies of angioplasty and stenting in this population are important, as the stroke risk on medical therapy is 12 % at 1 year and post-procedure stroke rates are similar to rates with medical treatment. There are many issues that will need to be resolved for stenting to offer any benefit, however. Procedural risks of hemorrhagic and ischemic stroke are unacceptably high. High-risk subgroups, potentially based on hemodynamic factors, will need to be identified for future interventional trials. Nevertheless, it is still reasonable to consider angioplasty and stenting for selected patients with multiple recurrent events despite aggressive medical management, but benefits are unclear at this time.
Details
- Title: Subtitle
- Stenting in Intracranial Stenosis: Current Controversies and Future Directions
- Creators
- Arindam Chatterjee - Department of Radiology Medical University of South Carolina Suite 210, 96 Jonathan Lucas St. Charleston SC 29425 USAColin Derdeyn - Department of Radiology, Mallinckrodt Institute of Radiology Washington University School of Medicine 510 South Kingshighway Blvd., Campus Box 8131 Saint Louis MO 63110 USA
- Resource Type
- Journal article
- Publication Details
- Current atherosclerosis reports, Vol.17(8), pp.1-9
- Publisher
- Springer US; New York
- DOI
- 10.1007/s11883-015-0527-4
- PMID
- 26104430
- ISSN
- 1523-3804
- eISSN
- 1534-6242
- Language
- English
- Date published
- 08/2015
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984013115002771
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