Stereotactic Radiosurgery or Fractionated Stereotactic Radiotherapy for Arteriovenous Malformation

Leila Maria Da Róz; Geovanne Pedro Mauro; Vinicius de Carvalho Gico; Eduardo Weltman; Evandro César de Souza; Eberval Gadelha Figueiredo; Manoel Jacobsen Teixeira

doi:10.1016/j.wneu.2023.05.075

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Stereotactic Radiosurgery or Fractionated Stereotactic Radiotherapy for Arteriovenous Malformation

Journal article

Peer reviewed

Stereotactic Radiosurgery or Fractionated Stereotactic Radiotherapy for Arteriovenous Malformation

Leila Maria Da Róz, Geovanne Pedro Mauro, Vinicius de Carvalho Gico, Eduardo Weltman, Evandro César de Souza, Eberval Gadelha Figueiredo and Manoel Jacobsen Teixeira

World neurosurgery, Vol.176, pp.e415-e419

08/2023

DOI: 10.1016/j.wneu.2023.05.075

PMID: 37245668

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Abstract

The best management for AVM, particularly high-grade ones and those that have been ruptured before, is still unknown. Data from prospective data lacks support for the best approach. We retrospectively review patients with AVM at a single institution that were treated with radiation or a combination of radiation and embolization. These patients were divided into two groups based on radiation fractionation: SRS and fSRS. One-hundred and thirty-five (135) patients were first assessed and 121 met study criteria. Mean age at treatment was 30.5 years, and most patients were male. The groups were otherwise balanced, except for nidus size. SRS group had smaller lesions (P > 0.005). SRS correlates to better chance of nidus occlusion and lesser chance of retreatment. Complications such as radionecrosis (5%) and bleeding after nidus occlusion (1 patient) were rare. Stereotactic radiosurgery plays an important role on the treatment of AVM. Whenever possible, SRS should be preferred. Data from prospective trials about larger and previously ruptured lesions are needed.

Arteriovenous malformation

Radiosurgery

Radiotherapy

Stereotactic

Details

Title: Subtitle: Stereotactic Radiosurgery or Fractionated Stereotactic Radiotherapy for Arteriovenous Malformation
Creators: Leila Maria Da Róz - Universidade de São Paulo
Geovanne Pedro Mauro - Universidade de São Paulo
Vinicius de Carvalho Gico - Instituto do Câncer do Estado de São Paulo
Eduardo Weltman - Universidade de São Paulo
Evandro César de Souza - Universidade de São Paulo
Eberval Gadelha Figueiredo - Universidade de São Paulo
Manoel Jacobsen Teixeira - Universidade de São Paulo
Resource Type: Journal article
Publication Details: World neurosurgery, Vol.176, pp.e415-e419
DOI: 10.1016/j.wneu.2023.05.075
PMID: 37245668
NLM abbreviation: World Neurosurg
ISSN: 1878-8750
eISSN: 1878-8769
Publisher: Elsevier Inc
Grant note: International Atomic Energy Agency (https://doi.org/10.13039/501100004493)
Language: English
Date published: 08/2023
Academic Unit: Radiation Oncology
Record Identifier: 9984914017302771

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