Journal article
Strain-relatedness of methicillin-resistant Staphylococcus aureus isolates recovered from patients with repeated infection
Clinical infectious diseases, Vol.46(8), pp.1241-1247
04/15/2008
DOI: 10.1086/529381
PMCID: PMC2723744
PMID: 18444862
Abstract
Invasive disease following methicillin-resistant Staphylococcus aureus (MRSA) detection is common, regardless of whether initial detection involves colonization or infection. We assessed the genetic relatedness of isolates obtained > or =2 weeks apart representing either repeated infections or colonization-infection sets to determine if infections are likely to be caused by previously harbored strains. We found that MRSA infection following initial colonization or infection is caused by the same strain in most cases, suggesting that a single successful attempt at decolonization may prevent the majority of later infection.
Details
- Title: Subtitle
- Strain-relatedness of methicillin-resistant Staphylococcus aureus isolates recovered from patients with repeated infection
- Creators
- Susan S Huang - Division of Infectious Diseases, University of California Irvine School of Medicine, Orange, CA 92868, USA. susan.huang@uci.eduDaniel J DiekemaDavid K WarrenGianna ZuccottiPatricia L WinokurShailesh TendolkarLinda BoykenRupak DattaRebecca M JonesMelissa A WardTanya AubreyAndrew B OnderdonkChristian GarciaRichard Platt
- Resource Type
- Journal article
- Publication Details
- Clinical infectious diseases, Vol.46(8), pp.1241-1247
- Publisher
- United States
- DOI
- 10.1086/529381
- PMID
- 18444862
- PMCID
- PMC2723744
- ISSN
- 1058-4838
- eISSN
- 1537-6591
- Grant note
- K23 AI064161 / NIAID NIH HHS K23 AI064161-04 / NIAID NIH HHS K23AI64161-01 / NIAID NIH HHS
- Language
- English
- Date published
- 04/15/2008
- Academic Unit
- Infectious Diseases; Pathology; Medicine Administration; Internal Medicine
- Record Identifier
- 9983986255302771
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