Streptococcus agalactiae Toxic Shock-Like Syndrome: Two Case Reports and Review of the Literature

Fadi Al Akhrass; Lina Abdallah; Steven Berger; Rami Hanna; Nina Reynolds; Shellie Thompson; Rabih Hallit; Patrick M Schlievert

doi:10.1097/MD.0b013e31827dea11

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Streptococcus agalactiae Toxic Shock-Like Syndrome: Two Case Reports and Review of the Literature

Journal article

Open access

Streptococcus agalactiae Toxic Shock-Like Syndrome: Two Case Reports and Review of the Literature

Fadi Al Akhrass, Lina Abdallah, Steven Berger, Rami Hanna, Nina Reynolds, Shellie Thompson, Rabih Hallit and Patrick M Schlievert

Medicine (Baltimore), Vol.92(1), pp.10-14

01/2013

DOI: 10.1097/MD.0b013e31827dea11

PMID: 23263717

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Abstract

We present 2 patients with Streptococcus agalactiae toxic shock-like syndrome and review another 11 well-reported cases from the literature. Streptococcal toxic shock-like syndrome is a devastating illness with a high mortality rate, therefore we stress the importance of early supportive management, antimicrobial therapy, and surgical intervention. Toxic shock-like syndrome is likely to be underestimated in patients with invasive Streptococcus agalactiae infection who present with shock. Early diagnosis requires high suspicion of the illness, along with a thorough mucocutaneous examination. Streptococcus agalactiae produces uncharacterized pyrogenic toxins, which explains the ability of the organism to cause toxic shock-like syndrome.

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Details

Title: Subtitle: Streptococcus agalactiae Toxic Shock-Like Syndrome: Two Case Reports and Review of the Literature
Creators: Fadi Al Akhrass - From the Department of Infectious Diseases (FAA, LA, SB, R Hanna, NR, ST), Pikeville Medical Center, Pikeville, Kentucky; Department of Infectious Diseases (R Hallit), Saint Michael’s Medical Center, Newark, New Jersey; and University of Minnesota Medical School (PMS), Minneapolis, Minnesota
Lina Abdallah - From the Department of Infectious Diseases (FAA, LA, SB, R Hanna, NR, ST), Pikeville Medical Center, Pikeville, Kentucky; Department of Infectious Diseases (R Hallit), Saint Michael’s Medical Center, Newark, New Jersey; and University of Minnesota Medical School (PMS), Minneapolis, Minnesota
Steven Berger - From the Department of Infectious Diseases (FAA, LA, SB, R Hanna, NR, ST), Pikeville Medical Center, Pikeville, Kentucky; Department of Infectious Diseases (R Hallit), Saint Michael’s Medical Center, Newark, New Jersey; and University of Minnesota Medical School (PMS), Minneapolis, Minnesota
Rami Hanna - From the Department of Infectious Diseases (FAA, LA, SB, R Hanna, NR, ST), Pikeville Medical Center, Pikeville, Kentucky; Department of Infectious Diseases (R Hallit), Saint Michael’s Medical Center, Newark, New Jersey; and University of Minnesota Medical School (PMS), Minneapolis, Minnesota
Nina Reynolds - From the Department of Infectious Diseases (FAA, LA, SB, R Hanna, NR, ST), Pikeville Medical Center, Pikeville, Kentucky; Department of Infectious Diseases (R Hallit), Saint Michael’s Medical Center, Newark, New Jersey; and University of Minnesota Medical School (PMS), Minneapolis, Minnesota
Shellie Thompson - From the Department of Infectious Diseases (FAA, LA, SB, R Hanna, NR, ST), Pikeville Medical Center, Pikeville, Kentucky; Department of Infectious Diseases (R Hallit), Saint Michael’s Medical Center, Newark, New Jersey; and University of Minnesota Medical School (PMS), Minneapolis, Minnesota
Rabih Hallit - From the Department of Infectious Diseases (FAA, LA, SB, R Hanna, NR, ST), Pikeville Medical Center, Pikeville, Kentucky; Department of Infectious Diseases (R Hallit), Saint Michael’s Medical Center, Newark, New Jersey; and University of Minnesota Medical School (PMS), Minneapolis, Minnesota
Patrick M Schlievert - From the Department of Infectious Diseases (FAA, LA, SB, R Hanna, NR, ST), Pikeville Medical Center, Pikeville, Kentucky; Department of Infectious Diseases (R Hallit), Saint Michael’s Medical Center, Newark, New Jersey; and University of Minnesota Medical School (PMS), Minneapolis, Minnesota
Resource Type: Journal article
Publication Details: Medicine (Baltimore), Vol.92(1), pp.10-14
DOI: 10.1097/MD.0b013e31827dea11
PMID: 23263717
NLM abbreviation: Medicine (Baltimore)
ISSN: 0025-7974
eISSN: 1536-5964
Publisher: Wolters Kluwer Health
Language: English
Date published: 01/2013
Academic Unit: Microbiology and Immunology; Internal Medicine
Record Identifier: 9984001213502771

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