Journal article
Stress Influences on Anoikis
Cancer prevention research (Philadelphia, Pa.), Vol.4(4), pp.481-485
04/2011
DOI: 10.1158/1940-6207.CAPR-10-0358
PMCID: PMC3074235
PMID: 21464029
Abstract
It long has been suspected that psychosocial factors affect cancer development and progression. Although the connections between stress and cancer causation are not strong, epidemiological and clinical studies have provided strong links between cancer progression and several stress-related factors including chronic stress, depression, and social isolation. Recent molecular and biological studies have identified specific signaling pathways that influence cancer growth and metastasis. In particular, stress hormones can have a significant impact on protecting cancer cells from undergoing the anoikis form of programmed cell death, thus, providing a mechanistic advantage for metastasis. This review provides an overview of the relationship between psychosocial factors and the avoidance of anoikis by cancer cells.
Details
- Title: Subtitle
- Stress Influences on Anoikis
- Creators
- Anil K Sood - Department of Gynecologic Oncology, M. D. Anderson Cancer Center, Houston, TexasSusan K Lutgendorf - Department of Psychology, University of Iowa, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Cancer prevention research (Philadelphia, Pa.), Vol.4(4), pp.481-485
- DOI
- 10.1158/1940-6207.CAPR-10-0358
- PMID
- 21464029
- PMCID
- PMC3074235
- NLM abbreviation
- Cancer Prev Res (Phila)
- ISSN
- 1940-6207
- eISSN
- 1940-6215
- Language
- English
- Date published
- 04/2011
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute; Obstetrics and Gynecology; Urology
- Record Identifier
- 9984065882102771
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