Journal article
Stress less: Viral mastery of the RNA G-quadruplex
Cell host & microbe, Vol.32(9), pp.1464-1465
09/11/2024
DOI: 10.1016/j.chom.2024.08.011
PMID: 39265533
Abstract
RNA G-quadruplexes are dynamically regulated during stress and infection. In this issue of Cell Host & Microbe, Schult et al.1 demonstrate that an RNA G-quadruplex conserved across orthoflaviviruses binds hnRNPH1 to mitigate the host stress response, highlighting the potential of this dynamic proviral RNA structure as a pan-flaviviral target.
RNA G-quadruplexes are dynamically regulated during stress and infection. In this issue of Cell Host & Microbe, Schult et al. demonstrate that an RNA G-quadruplex conserved across orthoflaviviruses binds hnRNPH1 to mitigate the host stress response, highlighting the potential of this dynamic proviral RNA structure as a pan-flaviviral target.
Details
- Title: Subtitle
- Stress less: Viral mastery of the RNA G-quadruplex
- Creators
- Sheila Gonzalez - Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, USAMaria G. Noval - Icahn School of Medicine at Mount SinaiJessica M. Tucker - Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Cell host & microbe, Vol.32(9), pp.1464-1465
- DOI
- 10.1016/j.chom.2024.08.011
- PMID
- 39265533
- NLM abbreviation
- Cell Host Microbe
- ISSN
- 1931-3128
- eISSN
- 1934-6069
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 09/11/2024
- Academic Unit
- Microbiology and Immunology
- Record Identifier
- 9984701559802771
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