Journal article
Stroke in octogenarians undergoing coronary artery surgery with and without cardiopulmonary bypass
The Annals of thoracic surgery, Vol.69(5), pp.1471-1475
05/2000
DOI: 10.1016/S0003-4975(00)01238-8
PMID: 10881825
Abstract
Background. Myocardial revascularization in elderly patients is associated with a morbidity and a mortality substantially higher than those observed in younger patients. The aim of this study was to analyze the potential benefits of coronary artery bypass grafting without cardiopulmonary bypass (CPB) for octogenarians.
Methods. Of 269 octogenarians who underwent coronary artery bypass grafting at our institution between January 1995 and May 1999, 172 had the operation with CPB (CPB group) and 97, without CPB (off-pump group). Revascularization of the circumflex system or right coronary artery were not considered contraindications to off-pump grafting. Demographic data, preoperative risk factors, comorbid conditions, angiographic findings, postoperative complications, and outcomes were compared.
Results. The groups were comparable for age, sex, Canadian Cardiovascular Society class, operative priority (elective, urgent, or emergent), preoperative risk factors, and left ventricular ejection fraction. A significantly higher proportion of reoperations was observed in the off-pump cohort (16 of 97, 16.5%) compared with the CPB cohort (8 of 172, 4.7%) (p = 0.002). There was a trend toward a higher graft-patient ratio in the CPB group (3.3 versus 1.8; p = not significant). Freedom from postoperative complications was significantly higher in the off-pump group than in the CPB group (83 of 97, 85.6%, versus 129 of 172, 75%; p = 0.04). The incidence of stroke was 0% in the off-pump cohort compared with 9.3% (16 of 172) in the CPB cohort (p < 0.0005). Although there was a trend toward higher 30-day and risk-adjusted mortality rates in the off-pump group than in the CPB group (10.3% versus 5.2% and 2.8% versus 1.8%, respectively), the differences were not significant. The length of hospitalization was slightly lower in the off-pump group (9.1 versus 10.8 days; p = not significant).
Conclusions. This investigation suggests that patients 80 years of age and older undergoing off-pump coronary artery bypass grafting can experience significantly lower rates of perioperative stroke and overall complications compared with those undergoing the same procedure with CPB, although a trend toward higher mortality rates was observed in the off-pump group.
Details
- Title: Subtitle
- Stroke in octogenarians undergoing coronary artery surgery with and without cardiopulmonary bypass
- Creators
- Marco Ricci - Division of Cardiothoracic Surgery and the Center for Minimally Invasive Cardiac Surgery, The Buffalo General Hospital, SUNY at Buffalo, Buffalo, New York, USAHratch L Karamanoukian - Division of Cardiothoracic Surgery and the Center for Minimally Invasive Cardiac Surgery, The Buffalo General Hospital, SUNY at Buffalo, Buffalo, New York, USAReginald Abraham - Division of Cardiothoracic Surgery and the Center for Minimally Invasive Cardiac Surgery, The Buffalo General Hospital, SUNY at Buffalo, Buffalo, New York, USAKurt Von Fricken - Division of Cardiothoracic Surgery and the Center for Minimally Invasive Cardiac Surgery, The Buffalo General Hospital, SUNY at Buffalo, Buffalo, New York, USAGiuseppe D’Ancona - Division of Cardiothoracic Surgery and the Center for Minimally Invasive Cardiac Surgery, The Buffalo General Hospital, SUNY at Buffalo, Buffalo, New York, USASue Choi - Division of Cardiothoracic Surgery and the Center for Minimally Invasive Cardiac Surgery, The Buffalo General Hospital, SUNY at Buffalo, Buffalo, New York, USAJacob Bergsland - Division of Cardiothoracic Surgery and the Center for Minimally Invasive Cardiac Surgery, The Buffalo General Hospital, SUNY at Buffalo, Buffalo, New York, USATomas A Salerno - Division of Cardiothoracic Surgery and the Center for Minimally Invasive Cardiac Surgery, The Buffalo General Hospital, SUNY at Buffalo, Buffalo, New York, USA
- Resource Type
- Journal article
- Publication Details
- The Annals of thoracic surgery, Vol.69(5), pp.1471-1475
- Publisher
- Elsevier Inc
- DOI
- 10.1016/S0003-4975(00)01238-8
- PMID
- 10881825
- ISSN
- 0003-4975
- eISSN
- 1552-6259
- Language
- English
- Date published
- 05/2000
- Academic Unit
- Cardiothoracic Surgery
- Record Identifier
- 9984323059402771
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