Journal article
Structural water in oxidized and reduced horse heart cytochrome c
Nature structural & molecular biology, Vol.1(6), pp.378-382
06/01/1994
DOI: 10.1038/nsb0694-378
PMID: 7664051
Abstract
The existence of structural water in the interior of both oxidized and reduced horse-heart cytochrome c in solution is demonstrated using nuclear magnetic resonance spectroscopy. Six water molecules have been located in ferrocytochrome c and five in ferricytochrome c, with residence times greater than a few hundred picoseconds. Two water molecules are located in the haem crevice, one of which is found to undergo a large change in position with a change of oxidation state. Both of these observations indicate that buried structural waters in the haem crevice have, by microscopic dielectric effects, significant roles in the setting of the solvent reorganization energy associated with electron transfer.
Details
- Title: Subtitle
- Structural water in oxidized and reduced horse heart cytochrome c
- Creators
- Phoebe Xiurong QiJeffrey L UrbauerErnesto J FuentesMary Frances LeopoldA. Joshua Wand
- Resource Type
- Journal article
- Publication Details
- Nature structural & molecular biology, Vol.1(6), pp.378-382
- DOI
- 10.1038/nsb0694-378
- PMID
- 7664051
- ISSN
- 1545-9993
- eISSN
- 1545-9985
- Language
- English
- Date published
- 06/01/1994
- Academic Unit
- Biochemistry and Molecular Biology
- Record Identifier
- 9984024559102771
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