Structure of DNA polymerase ζ: capturing the getaway driver

M Todd Washington; Melissa S Gildenberg

doi:10.1038/s41594-020-0502-9

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Structure of DNA polymerase ζ: capturing the getaway driver

Journal article

Peer reviewed

Structure of DNA polymerase ζ: capturing the getaway driver

M Todd Washington and Melissa S Gildenberg

Nature structural & molecular biology, Vol.27(10), pp.1-2

10/01/2020

DOI: 10.1038/s41594-020-0502-9

PMCID: PMC8163099

PMID: 32843752

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https://www.ncbi.nlm.nih.gov/pmc/articles/8163099View

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Abstract

During translesion synthesis, eukaryotic DNA polymerase ζ carries out extension from a wide range of DNA lesions. Elucidation of the cryo-EM structure of polymerase ζ reveals how the enzyme catalyzes DNA strand synthesis beyond the lesion.

Details

Title: Subtitle: Structure of DNA polymerase ζ: capturing the getaway driver
Creators: M Todd Washington - University of Iowa
Melissa S Gildenberg - University of Iowa
Resource Type: Journal article
Publication Details: Nature structural & molecular biology, Vol.27(10), pp.1-2
DOI: 10.1038/s41594-020-0502-9
PMID: 32843752
PMCID: PMC8163099
NLM abbreviation: Nat Struct Mol Biol
ISSN: 1545-9993
eISSN: 1545-9985
Language: English
Date published: 10/01/2020
Academic Unit: Radiation Oncology; Biochemistry and Molecular Biology
Record Identifier: 9984293086202771

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