Structure of the HapX:CCAAT-binding protein complex with DNA: A piece of the puzzle revealed

W Scott Moye-Rowley

doi:10.1016/j.str.2022.05.018

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Structure of the HapX:CCAAT-binding protein complex with DNA: A piece of the puzzle revealed

Journal article

Open access

Peer reviewed

Structure of the HapX:CCAAT-binding protein complex with DNA: A piece of the puzzle revealed

W Scott Moye-Rowley

Structure (London), Vol.30(7), pp.917-919

07/07/2022

DOI: 10.1016/j.str.2022.05.018

PMCID: PMC9830593

PMID: 35803238

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Abstract

DNA recognition by the HapX transcription factor from Aspergillus species requires the presence of a heterotrimeric DNA-binding protein called the CCAAT-binding complex (CBC). In this issue of Structure, Huber and colleagues illuminate the structural basis for the multivalent binding of the CBC, HapX, and the DNA target site.

Details

Title: Subtitle: Structure of the HapX:CCAAT-binding protein complex with DNA: A piece of the puzzle revealed
Creators: W Scott Moye-Rowley - Roy J. and Lucille A. Carver College of Medicine
Resource Type: Journal article
Publication Details: Structure (London), Vol.30(7), pp.917-919
DOI: 10.1016/j.str.2022.05.018
PMID: 35803238
PMCID: PMC9830593
NLM abbreviation: Structure
ISSN: 0969-2126
eISSN: 1878-4186
Language: English
Date published: 07/07/2022
Academic Unit: Molecular Physiology and Biophysics; Internal Medicine
Record Identifier: 9984297498202771

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