Study of the afferent pathways from the rectum with a new distention control device

V LOENING-BAUCKE; R. H ANDERSON; T YAMADA; Yi-Xiu Zhu

doi:10.1212/WNL.45.8.1510

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Study of the afferent pathways from the rectum with a new distention control device

Journal article

Peer reviewed

Study of the afferent pathways from the rectum with a new distention control device

V LOENING-BAUCKE, R. H ANDERSON, T YAMADA and Yi-Xiu Zhu

Neurology, Vol.45(8), pp.1510-1516

1995

DOI: 10.1212/WNL.45.8.1510

PMID: 7644050

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Abstract

Quantitative studies of the afferent pathways from hollow viscera have been limited by the lack of an easily controlled, reproducible visceral stimulus.We adapted a slow distention device to allow for rapid distention to study the afferent pathways from the rectum. The device produced a pressure increase of 10 mm Hg in 42 msec and of 20 mm Hg in 60 msec. We recorded cerebral evoked potentials (EPs) after rectal balloon distention in 17 healthy subjects. Several averages of 25 to 50 rectal distentions at 0.17-Hz frequency were recorded. The responses consisted of multiple peaks within 200 msec after stimulation. The mean latency of the initial positive peak was 44 msec, suggesting that a myelinated pathway was stimulated with mechanical rectal distention. Our device produced reliable and repeatable EPs that were independent of balloon characteristics or rectal pressures. EP recording after rectal stimulation may become a useful technique for the physiologic investigation of disorders such as fecal incontinence, constipation, irritable bowel syndrome, and chronic intestinal pseudo-obstruction.

Nervous System

Biological and medical sciences

Electrodiagnosis. Electric activity recording

Investigative techniques, diagnostic techniques (general aspects)

Medical sciences

Details

Title: Subtitle: Study of the afferent pathways from the rectum with a new distention control device
Creators: V LOENING-BAUCKE - Univ. Iowa, dep. pediatrics, Iowa City IA 52242, United States
R. H ANDERSON - Univ. Iowa, dep. pediatrics, Iowa City IA 52242, United States
T YAMADA - Univ. Iowa, dep. pediatrics, Iowa City IA 52242, United States
Yi-Xiu Zhu - Univ. Iowa, dep. pediatrics, Iowa City IA 52242, United States
Resource Type: Journal article
Publication Details: Neurology, Vol.45(8), pp.1510-1516
Publisher: Lippincott Williams & Wilkins; Hagerstown, MD
DOI: 10.1212/WNL.45.8.1510
PMID: 7644050
ISSN: 0028-3878
eISSN: 1526-632X
Language: English
Date published: 1995
Academic Unit: Neurology; Stead Family Department of Pediatrics
Record Identifier: 9984020734502771

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