Journal article
Subacute radiation dermatitis from fluoroscopy during coronary artery stenting: Evidence for cytotoxic lymphocyte mediated apoptosis
Journal of the American Academy of Dermatology, Vol.38(2), pp.333-336
1998
DOI: 10.1016/S0190-9622(98)70577-8
PMID: 9486710
Abstract
A patient with fluoroscopy-induced subacute radiation dermatitis is described. Her biopsy specimen showed vacuolar change and necrotic keratinocytes with lymphocytes in direct apposition, or “satellitosis.” Lymphocytes in the dermis and infiltrating the epidermis were predominantly CD8
+ and a number of the lymphocytes stained for TIA-1, a cytotoxic granule protein in T-cells and natural killer cells, that appears to be involved in the induction of apoptosis. Our findings suggest cytotoxic lymphocyte mediated apoptosis is involved in the pathogenesis of subacute radiation dermatitis. (J Am Acad Dermatol 1998;38:333-6.)
Details
- Title: Subtitle
- Subacute radiation dermatitis from fluoroscopy during coronary artery stenting: Evidence for cytotoxic lymphocyte mediated apoptosis
- Creators
- Mary Seabury StoneKristi J RobsonPhilip E LeBoit
- Resource Type
- Journal article
- Publication Details
- Journal of the American Academy of Dermatology, Vol.38(2), pp.333-336
- DOI
- 10.1016/S0190-9622(98)70577-8
- PMID
- 9486710
- NLM abbreviation
- J Am Acad Dermatol
- ISSN
- 0190-9622
- eISSN
- 1097-6787
- Publisher
- Mosby, Inc
- Language
- English
- Date published
- 1998
- Academic Unit
- Dermatology; Pathology
- Record Identifier
- 9984025320902771
Metrics
12 Record Views