Substantiated childhood maltreatment and young adulthood cannabis use disorders: A pre-birth cohort study

Amanuel Alemu Abajobir; Jake Moses Najman; Gail Williams; Lane Strathearn; Alexandra Clavarino; Steve Kisely

doi:10.1016/j.psychres.2017.06.017

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Substantiated childhood maltreatment and young adulthood cannabis use disorders: A pre-birth cohort study

Journal article

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Substantiated childhood maltreatment and young adulthood cannabis use disorders: A pre-birth cohort study

Amanuel Alemu Abajobir, Jake Moses Najman, Gail Williams, Lane Strathearn, Alexandra Clavarino and Steve Kisely

Psychiatry research, Vol.256, pp.21-31

10/2017

DOI: 10.1016/j.psychres.2017.06.017

PMCID: PMC5603409

PMID: 28622571

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Abstract

This study investigates the association between exposure to prospectively-substantiated childhood maltreatment between 0 and 14 years of age and lifetime cannabis use, abuse and dependence reported at 21 years. Data were taken from 2526 (51.6% female) participants in the Mater Hospital-University of Queensland Study of Pregnancy, a pre-birth, prospective, cohort study. Prospectively-substantiated cases of childhood maltreatment, reported to the government child protection agencies between 0 and 14 years of age, were linked to CIDI DSM-IV self-report data from the 21-year follow-up. Exposure to any childhood maltreatment, and childhood neglect in particular, predicted subsequent cannabis abuse with adjusted odds ratios (AORs) of 1.79 and 2.62, respectively. Any childhood maltreatment, physical abuse, emotional abuse and neglect predicted cannabis dependence with AORs of 2.47, 2.81, 2.44 and 2.68, respectively. The associations for an early age of onset of cannabis abuse and dependence were significant and consistent for maltreated children. In addition, frequency of maltreatment substantiations predicted cannabis abuse, dependence and an early age of onset of these disorders. The AORs for cannabis ever use without any DSM-IV cannabis disorder were 1.78 for any maltreatment and 2.15 for emotional abuse. Any childhood maltreatment and neglect predicted lifetime ever cannabis use, as well as cannabis use disorder. There was little evidence for any interaction between gender and different forms of childhood maltreatment and its association with cannabis use disorders. Physical abuse, emotional abuse and neglect, as well as multiple episodes of maltreatment independently predicted cannabis use disorders. •Subthreshold, persistent, early age of onset of, and cannabis use without disorders, were common problems of maltreatment.•These associations were also strong for more frequent episodes of childhood maltreatment.•There was no gender-any childhood maltreatment interaction effect on cannabis use disorders.

Cannabis use disorders

Childhood abuse

Neglect

Longitudinal study

Details

Title: Subtitle: Substantiated childhood maltreatment and young adulthood cannabis use disorders: A pre-birth cohort study
Creators: Amanuel Alemu Abajobir - Faculty of Medicine, School of Public Health, The University of Queensland, Public Health Building, Herston 4006, Queensland, Australia
Jake Moses Najman - Faculty of Medicine, School of Public Health, The University of Queensland, Public Health Building, Herston 4006, Queensland, Australia
Gail Williams - Faculty of Medicine, School of Public Health, The University of Queensland, Public Health Building, Herston 4006, Queensland, Australia
Lane Strathearn - Stead Family Department of Pediatrics, Division of Developmental and Behavioral Pediatrics, University of Iowa, Iowa City, IA, USA
Alexandra Clavarino - Faculty of Health and Behavioral Sciences, School of Pharmacy, The University of Queensland, Woolloongabba 4102, Queensland, Australia
Steve Kisely - Faculty of Medicine, School of Medicine, University of Queensland, Princess Alexandra Hospital, Woolloongabba 4102, Queensland, Australia
Resource Type: Journal article
Publication Details: Psychiatry research, Vol.256, pp.21-31
DOI: 10.1016/j.psychres.2017.06.017
PMID: 28622571
PMCID: PMC5603409
NLM abbreviation: Psychiatry Res
ISSN: 0165-1781
eISSN: 1872-7123
Publisher: Elsevier B.V
Grant note: DOI: 10.13039/501100000925, name: National Health and Medical Research Council, award: 1009460; DOI: 10.13039/501100000923, name: Australian Research Council; name: U.S. National Institute of Drug Abuse, award: 2R01DA026437
Language: English
Date published: 10/2017
Academic Unit: Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Developmental and Behavioral Pediatrics; Neuroscience and Pharmacology
Record Identifier: 9984040283802771

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