Journal article
Success of combined cataract extraction plus excimer laser trabeculotomy exceeds that of combined ab interno trabeculectomy with the trabectome or cataract extraction alone
International ophthalmology, Vol.40(3), pp.529-537
03/01/2020
DOI: 10.1007/s10792-019-01191-9
PMID: 31724109
Abstract
Purpose To determine the efficacy of cataract surgery alone and combined with two minimally invasive glaucoma surgery (MIGS) procedures (phaco-ELT and phaco-aiT). Methods Data was collected from 12/2007 to 02/2012 in this retrospective, non-randomized, comparative single surgery center study. Reduction in IOP and hypotensive medication (AGD), change in visual acuity, success rates, and complications were computed by comparing preoperative data with data at 1 year postoperatively. Results A total of 245 eyes of 245 subjects were included. Study eyes underwent phaco alone (38 eye) or combined phaco-ELT (105 eye) and phaco-aiT (102 eye). Phaco alone, combined phaco-ELT, and combined phaco-aiT lowered IOP by 1.5 +/- 4.0 mmHg, 4.3 +/- 5.6, and 5.3 +/- 4.5 mmHg, respectively (P < 0.01). Survival time of phaco-ELT outreached survival time of phaco alone and combined phaco-aiT (20.6 +/- 1.0 vs. 13.2 +/- 0.4 and 12.9 +/- 0.6 month, respectively). No serious complications or adverse events occurred. None of the cases required a subsequent procedure within the first year to lower IOP further. Conclusions All three surgical procedures lowered IOP and reduced medication. However, the IOP-lowering efficacy of the two combined MIGS procedures exceeded the effect of phaco alone. A combined phaco and MIGS procedures seem reasonable to consider whenever a cataract surgery in an eye with glaucoma or ocular hypertension is considered. In addition, the combined MIGS procedure effectively lowers IOP whenever a target IOP in the mid-teens is sufficient. In this study, the nonthermal phaco-ELT procedure showed superior efficacy at 1 year over phaco alone and phaco-aiT in the Kaplan-Meier statistics.
Details
- Title: Subtitle
- Success of combined cataract extraction plus excimer laser trabeculotomy exceeds that of combined ab interno trabeculectomy with the trabectome or cataract extraction alone
- Creators
- Lidija Jozic - University of ZurichJoachim MagnerJens Funk - University Hospital of ZurichMarc Toeteberg-Harms - Univ Hosp Zurich, Dept Ophthalmol, Frauenklinikstr 24, CH-8091 Zurich, Switzerland
- Resource Type
- Journal article
- Publication Details
- International ophthalmology, Vol.40(3), pp.529-537
- DOI
- 10.1007/s10792-019-01191-9
- PMID
- 31724109
- NLM abbreviation
- Int Ophthalmol
- ISSN
- 0165-5701
- eISSN
- 1573-2630
- Publisher
- Springer Nature
- Number of pages
- 9
- Language
- English
- Date published
- 03/01/2020
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984696572602771
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