Journal article
Successful Outcomes of Older Donors in Laparoscopic Donor Nephrectomy
Journal of endourology, Vol.24(10), pp.1593-1596
10/01/2010
DOI: 10.1089/end.2009.0679
PMID: 20836718
Abstract
Background and Purpose:
Healthy older living donors (>50 years) are helping meet increasing demands for kidney transplantation. Live donor grafts perform better than cadaveric donor grafts; however, concern surrounds the expected nephron loss of the donors as well as the relative safety to the donor. We examined the effect age had on living laparoscopic donor and recipient outcomes at a single institution.
Patients and Methods:
We retrospectively reviewed records of 101 patients who underwent laparoscopic donor nephrectomy (LDN) from October 2001 to December 2005. Twenty-nine (29%) who were aged 50 years or older, denoted as the “older” group, were compared with the remaining 72 (71%) donors who were younger than 50 years and served as controls. Perioperative and follow-up data were analyzed for both groups.
Results:
The mean age at the time of donation was 36.1 and 54.3 years for control and older donors, respectively (
P
< 0.001). Baseline mean creatinine level was 0.82 mg/dL for controls and 0.84 mg/dL for older donors (
P
= 0.78). Complications in controls and the older group were 18% and 17%, respectively. One-year transplant survival was 100% for the controls and 96% for the older group. Average creatinine level at longer follow-up of 19 months for controls and 23 months for the older group (
P
= 0.34) was 1.22 mg/dL and 1.16 mg/dL, respectively (
P
= 0.535).
Conclusion:
LDN in donors older than 50 years of age appears safe and demonstrates similar outcomes compared with the control cohort of patients younger than 50 years. Age between 50 and 65 years should not exclude a potential donor who otherwise satisfies donor nephrectomy criteria.
Details
- Title: Subtitle
- Successful Outcomes of Older Donors in Laparoscopic Donor Nephrectomy
- Creators
- David A. Duchene - University of Kansas Medical CenterDaniel Y. Woodruff - University of KansasBrian L. Gallagher - Iowa ClinicHoward A. Aubert - University of IowaDaniel Katz - University of IowaTy B. Dunn - University of MinnesotaHoward N. Winfield - Urology Associates
- Resource Type
- Journal article
- Publication Details
- Journal of endourology, Vol.24(10), pp.1593-1596
- Publisher
- Mary Ann Liebert, Inc
- DOI
- 10.1089/end.2009.0679
- PMID
- 20836718
- ISSN
- 0892-7790
- eISSN
- 1557-900X
- Language
- English
- Date published
- 10/01/2010
- Academic Unit
- Surgery
- Record Identifier
- 9984322933302771
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