Successful medical management of a neonate with spontaneous splenic rupture and severe hemophilia A

Sherif M Badawy; Jenna Rossoff; Sushmita Yallapragada; Robert I Liem; Anjali A Sharathkumar

doi:10.1016/j.hemonc.2016.04.001

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Successful medical management of a neonate with spontaneous splenic rupture and severe hemophilia A

Journal article

Open access

Successful medical management of a neonate with spontaneous splenic rupture and severe hemophilia A

Sherif M Badawy, Jenna Rossoff, Sushmita Yallapragada, Robert I Liem and Anjali A Sharathkumar

Hematology/oncology and stem cell therapy, Vol.10(1), pp.29-32

03/2017

DOI: 10.1016/j.hemonc.2016.04.001

PMID: 27178624

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Abstract

Splenic rupture in neonates is a rare event, usually occurring in the setting of underlying predisposing conditions. Here, we present the case of a term neonate who presented with worsening anemia in the setting of known hemolytic disease during the newborn period and was later found to have a spontaneous splenic rupture. He was subsequently diagnosed with severe hemophilia A, and was managed medically with recombinant factor VIII replacement therapy without any surgical intervention. This is the first reported case of a neonate who had spontaneous splenic rupture and severe hemophilia A, and underwent successful medical treatment without any surgical intervention.

Neonate

Factor VIII deficiency

Splenic rupture

Hemophilia A

Details

Title: Subtitle: Successful medical management of a neonate with spontaneous splenic rupture and severe hemophilia A
Creators: Sherif M Badawy - Department of Pediatrics, Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Jenna Rossoff - Department of Pediatrics, Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Sushmita Yallapragada - Department of Pediatrics, Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Robert I Liem - Department of Pediatrics, Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Anjali A Sharathkumar - Department of Pediatrics, Division of Hematology, Oncology and Stem Cell Transplantation, University of Iowa Children’s Hospital, Iowa City, IA, USA
Resource Type: Journal article
Publication Details: Hematology/oncology and stem cell therapy, Vol.10(1), pp.29-32
DOI: 10.1016/j.hemonc.2016.04.001
PMID: 27178624
NLM abbreviation: Hematol Oncol Stem Cell Ther
ISSN: 1658-3876
Publisher: Elsevier Ltd
Language: English
Date published: 03/2017
Academic Unit: Stead Family Department of Pediatrics; Hematology/Oncology
Record Identifier: 9984093501402771

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