Journal article
Successful program to prevent aspergillus infections in children undergoing marrow transplantation : use of nasal amphotericin
Bone marrow transplantation (Basingstoke), Vol.19(1), pp.43-47
1997
DOI: 10.1038/sj.bmt.1700618
PMID: 9012930
Abstract
Aspergillus infections in pediatric bone marrow transplant (BMT) patients are usually fatal. We began the use of a prophylactic nasal spray of amphotericin in 1990. This nasal spray was provided in addition to low-dose intravenous amphotericin. During the time of this study, the number of fatal cases of aspergillus in the pediatric BMT population was reduced significantly from 13.8% to 1.8% (P < 0.0025) thereby suggesting that the use of nasal amphotericin in this population helps to prevent fatal aspergillus infections. The lack of significant side-effects and the ease of administration make this a very helpful preventive measure in the supportive care of pediatric bone marrow transplant patients.
Details
- Title: Subtitle
- Successful program to prevent aspergillus infections in children undergoing marrow transplantation : use of nasal amphotericin
- Creators
- M. E Trigg - Pediatric Bone Marrow Transplant Program, Department of Pediatrics, The University of Iowa Hospitals and Clinics, Iowa City, IA, United StatesD Morgan - University of Iowa Hospitals and ClinicsT. L Burns - University of IowaH Kook - University of IowaS. L Rumelhart - University of IowaM. D Holida - Pediatric Bone Marrow Transplant Program, Department of Pediatrics, The University of Iowa Hospitals and Clinics, Iowa City, IA, United StatesR. H Giller - University of Colorado Denver
- Resource Type
- Journal article
- Publication Details
- Bone marrow transplantation (Basingstoke), Vol.19(1), pp.43-47
- Publisher
- Nature Publishing Group
- DOI
- 10.1038/sj.bmt.1700618
- PMID
- 9012930
- ISSN
- 0268-3369
- eISSN
- 1476-5365
- Language
- English
- Date published
- 1997
- Academic Unit
- Epidemiology; Fraternal Order of Eagles Diabetes Research Center; Neuroscience and Pharmacology
- Record Identifier
- 9984364402202771
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