Journal article
Successful treatment of an unresectable choroid plexus carcinoma in a patient with Li-Fraumeni syndrome
Journal of pediatric hematology/oncology, Vol.27(1), pp.46-49
01/2005
DOI: 10.1097/01.mph.0000152569.60694.1f
PMID: 15654279
Abstract
Choroid plexus carcinoma (CPC) is an uncommon central nervous system tumor requiring complete surgical excision for favorable outcome. The authors report the successful treatment of a 2-year-old patient with widely disseminated CPC and Li-Fraumeni syndrome. Following a partial resection of the tumor the patient received chemotherapy consisting of cyclophosphamide, etoposide, and carboplatin. There were no additional surgical procedures and radiation was not administered. Remarkably, the patient remains without evidence of active disease more than 3 years from the completion of therapy. Additional studies are necessary to determine whether this treatment plan can be beneficial to other patients with CPC and whether the patient's p53 mutation had an effect on outcome.
Details
- Title: Subtitle
- Successful treatment of an unresectable choroid plexus carcinoma in a patient with Li-Fraumeni syndrome
- Creators
- David S Dickens - Division of Hematology/Oncology, Department of Pediatrics, DeVos Children's Hospital, Grand Rapids, Michigan, USAJudith A DothageRichard L HeidemanEdgar T BallardPaul T Jubinsky
- Resource Type
- Journal article
- Publication Details
- Journal of pediatric hematology/oncology, Vol.27(1), pp.46-49
- DOI
- 10.1097/01.mph.0000152569.60694.1f
- PMID
- 15654279
- ISSN
- 1077-4114
- eISSN
- 1536-3678
- Language
- English
- Date published
- 01/2005
- Academic Unit
- Stead Family Department of Pediatrics; Hematology/Oncology
- Record Identifier
- 9984093492802771
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