Journal article
Sudden death in a patient with bone marrow transplant by a fungus among us
BMJ case reports, Vol.2014(nov12 1), pp.bcr2014207403-bcr2014207403
2014
DOI: 10.1136/bcr-2014-207403
PMCID: PMC4244385
PMID: 25391828
Abstract
Mucormycosis is rare, presenting as breakthrough infection among haematological and transplant patients on prophylaxis with voriconazole. We report an unusual presentation of this infection, that which is pneumonia progressing to cardiac arrest. A 68-year-old woman with refractory acute myelogenous leukaemia on voriconazole prophylaxis was initially admitted for neutropenic fever and pneumonia. She was discharged improved on antibiotics and voriconazole for presumed aspergillosis. She returned after 1 month with the same presentation. She eventually improved on antibiotics and voriconazole, and eventually received bone marrow transplantation. Three days later, she developed pleuritic chest pain, dyspnoea, and hypoxia requiring intubation. An hour after intubation, the patient arrested and expired. Autopsy revealed Rhizopus pneumonitis with pulmonary infarction, and emboli to her cerebellum, heart, thyroid and kidney. Mucormycosis is an emerging, fatal infection that should be suspected in haematological and transplant patients who deteriorate on voriconazole.
Details
- Title: Subtitle
- Sudden death in a patient with bone marrow transplant by a fungus among us
- Creators
- Lemuel Non - Barnes-Jewish HospitalJoanna Paula Sta Cruz - Einstein Medical Center PhiladelphiaSherilyn Tuazon - Thomas Jefferson University Hospital
- Resource Type
- Journal article
- Publication Details
- BMJ case reports, Vol.2014(nov12 1), pp.bcr2014207403-bcr2014207403
- DOI
- 10.1136/bcr-2014-207403
- PMID
- 25391828
- PMCID
- PMC4244385
- NLM abbreviation
- BMJ Case Rep
- ISSN
- 1757-790X
- eISSN
- 1757-790X
- Language
- English
- Date published
- 2014
- Academic Unit
- Infectious Diseases; Internal Medicine
- Record Identifier
- 9984360049302771
Metrics
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