Journal article
Suitability of Dysphonia Measurements for Telemonitoring of Parkinson's Disease
IEEE transactions on biomedical engineering, Vol.56(4), pp.1015-1022
04/01/2009
DOI: 10.1109/TBME.2008.2005954
PMCID: PMC3051371
PMID: 21399744
Abstract
In this paper, we present an assessment of the practical value of existing traditional and nonstandard measures for discriminating healthy people from people with Parkinson's disease (PD) by detecting dysphonia. We introduce a new measure of dysphonia, pitch period entropy (PPE), which is robust to many uncontrollable confounding effects including noisy acoustic environments and normal, healthy variations in voice frequency. We collected sustained phonations from 31 people, 23 with PD. We then selected ten highly uncorrelated measures, and an exhaustive search of all possible combinations of these measures finds four that in combination lead to overall correct classification performance of 91.4%, using a kernel support vector machine. In conclusion, we find that nonstandard methods in combination with traditional harmonics-to-noise ratios are best able to separate healthy from PD subjects. The selected nonstandard methods are robust to many uncontrollable variations in acoustic environment and individual subjects, and are thus well suited to telemonitoring applications.
Details
- Title: Subtitle
- Suitability of Dysphonia Measurements for Telemonitoring of Parkinson's Disease
- Creators
- Max A. Little - University of OxfordPatrick E. McSharry - University of OxfordEric J. Hunter - Denver Center for the Performing ArtsJennifer Spielman - Denver Center for the Performing ArtsLorraine O. Ramig - Denver Center for the Performing Arts
- Resource Type
- Journal article
- Publication Details
- IEEE transactions on biomedical engineering, Vol.56(4), pp.1015-1022
- DOI
- 10.1109/TBME.2008.2005954
- PMID
- 21399744
- PMCID
- PMC3051371
- NLM abbreviation
- IEEE Trans Biomed Eng
- ISSN
- 0018-9294
- eISSN
- 1558-2531
- Publisher
- IEEE
- Number of pages
- 8
- Grant note
- NIH-NIDCD R01-DC1150 / National Institute of Health (NIH); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Language
- English
- Date published
- 04/01/2009
- Academic Unit
- Communication Sciences and Disorders
- Record Identifier
- 9984446069502771
Metrics
19 Record Views