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Sulindac-Induced Aseptic Meningitis
Journal article   Peer reviewed

Sulindac-Induced Aseptic Meningitis

Zuhair K Ballas and Sam T Donta
Archives of internal medicine (1960), Vol.142(1), pp.165-166
01/01/1982
DOI: 10.1001/archinte.1982.00340140167031
PMID: 7053720

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Abstract

• A 22-year-old woman with systemic lupus erythematosus experienced generalized pruritus, shortness of breath, pleuritic chest pain, visual blurring, severe photophobia, a stiff neck, an occipital headache, and a temperature of 39.4 °C within one hour after taking sulindac (Clinoril). Findings from a CSF examination disclosed a notable elevation of protein and a polymorphonuclear pleocytosis. All symptoms disappeared within 24 hours. Inhibition of prostaglandin synthesis did not seem to be the mechanism of this adverse reaction, since the patient tolerated aspirin.(Arch Intern Med 1982;142:165-166)

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