Journal article
Sulpinines A-C and secopenitrem B: new antiinsectan metabolites from the sclerotia of Aspergillus sulphureus
Journal of organic chemistry, Vol.57(7), pp.2066-2071
03/01/1992
DOI: 10.1021/jo00033a030
Abstract
Extracts from the sclerotia of Aspergillus sulphureus have yielded four new antiinsectan compounds of the paspaline/penitrem class (2–5). These metabolites were isolated by a combination of chromatographic techniques. The structures were determined primarily by analysis of various NMR experiments and also by comparison to the structurally related penitrems. Sulpinine C contains an unusual eight-membered-ring lactam and possesses a ring system previously unreported as part of a natural product. The three indole metabolites (2,3, and 5) exhibit potent activity against the lepidopteran crop pest Helicoverpa zea. © 1992, American Chemical Society. All rights reserved.
Details
- Title: Subtitle
- Sulpinines A-C and secopenitrem B: new antiinsectan metabolites from the sclerotia of Aspergillus sulphureus
- Creators
- Jodi A LaaksoJames B GloerDonald T WicklowPatrick F Dowd
- Resource Type
- Journal article
- Publication Details
- Journal of organic chemistry, Vol.57(7), pp.2066-2071
- Publisher
- American Chemical Society
- DOI
- 10.1021/jo00033a030
- ISSN
- 0022-3263
- eISSN
- 1520-6904
- Language
- English
- Date published
- 03/01/1992
- Academic Unit
- Chemistry
- Record Identifier
- 9984216605502771
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