Summary of the Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation

Steven J Chadban; Curie Ahn; David A Axelrod; Bethany J Foster; Bertram L Kasiske; Vijah Kher; Deepali Kumar; Rainer Oberbauer; Julio Pascual; Helen L Pilmore; James R Rodrigue; Dorry L Segev; Neil S Sheerin; Kathryn J Tinckam; Germaine Wong; Ethan M Balk; Craig E Gordon; Amy Earley; Valerie Rofeberg; Gregory A Knoll

doi:10.1097/TP.0000000000003137

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Summary of the Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation

Journal article

Open access

Peer reviewed

Summary of the Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation

Steven J Chadban, Curie Ahn, David A Axelrod, Bethany J Foster, Bertram L Kasiske, Vijah Kher, Deepali Kumar, Rainer Oberbauer, Julio Pascual, Helen L Pilmore, …

Transplantation, Vol.104(4), pp.708-714

04/2020

DOI: 10.1097/TP.0000000000003137

PMCID: PMC7147399

PMID: 32224812

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Abstract

The 2020 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation is intended to assist health care professionals worldwide who evaluate and manage potential candidates for deceased or living donor kidney transplantation. This guideline addresses general candidacy issues such as access to transplantation, patient demographic and health status factors, immunological and psychosocial assessment. The roles of various risk factors and comorbid conditions governing an individual's suitability for transplantation such as adherence, tobacco use, diabetes, obesity, perioperative issues, causes of kidney failure, infections, malignancy, pulmonary disease, cardiac and peripheral arterial disease, neurologic disease, gastrointestinal and liver disease, hematologic disease, and bone and mineral disorder are also addressed. This guideline provides recommendations for evaluation of individual aspects of a candidate's profile such that each risk factor and comorbidity are considered separately. The goal is to assist the clinical team to assimilate all data relevant to an individual, consider this within their local health context, and make an overall judgment on candidacy for transplantation. The guideline development process followed the Grades of Recommendation Assessment, Development, and Evaluation (GRADE) approach. Guideline recommendations are primarily based on systematic reviews of relevant studies and our assessment of the quality of that evidence. The strengths of recommendations are provided in the full report. Limitations of the evidence are discussed with differences from previous guidelines noted and suggestions for future research are also provided.

Clinical Decision-Making

Consensus

Donor Selection - standards

Evidence-Based Medicine - standards

Health Status

Humans

Kidney Transplantation - adverse effects

Kidney Transplantation - standards

Living Donors - supply & distribution

Practice Guidelines as Topic - standards

Risk Assessment

Risk Factors

Transplant Recipients

Treatment Outcome

Details

Title: Subtitle: Summary of the Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation
Creators: Steven J Chadban - Royal Prince Alfred Hospital
Curie Ahn - Seoul National University
David A Axelrod - University of Iowa
Bethany J Foster - McGill University Health Centre
Bertram L Kasiske - Hennepin County Medical Center
Vijah Kher - Medanta The Medicity
Deepali Kumar - University Health Network
Rainer Oberbauer - Medical University of Vienna
Julio Pascual - Hospital Del Mar
Helen L Pilmore - Auckland City Hospital
James R Rodrigue - Beth Israel Deaconess Medical Center
Dorry L Segev - Johns Hopkins Medicine
Neil S Sheerin - Newcastle University
Kathryn J Tinckam - University of Toronto
Germaine Wong - The University of Sydney
Ethan M Balk - Brown University
Craig E Gordon - Tufts Medical Center
Amy Earley - Evidera, Waltham, MA, USA.
Valerie Rofeberg - Brown University
Gregory A Knoll - Ottawa Hospital
Resource Type: Journal article
Publication Details: Transplantation, Vol.104(4), pp.708-714
DOI: 10.1097/TP.0000000000003137
PMID: 32224812
PMCID: PMC7147399
NLM abbreviation: Transplantation
ISSN: 0041-1337
eISSN: 1534-6080
Language: English
Date published: 04/2020
Academic Unit: Surgery
Record Identifier: 9984322940702771

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