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Superior vena cava isolation using a pentaspline pulsed-field ablation catheter: feasibility and safety in patients undergoing atrial fibrillation catheter ablation
Journal article   Peer reviewed

Superior vena cava isolation using a pentaspline pulsed-field ablation catheter: feasibility and safety in patients undergoing atrial fibrillation catheter ablation

Pierre Ollitrault, Corentin Chaumont, Jonaz Font, Martin Manninger, Sergio Conti, Paweł T Matusik, Bart A Mulder, Virginie Ferchaud, Arnaud Pellissier, Mayane Al Khoury, …
Europace (London, England), Vol.26(7), euae160
07/02/2024
DOI: 10.1093/europace/euae160
PMCID: PMC11252500
PMID: 38875490

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Abstract

Aims Superior vena cava (SVC) isolation during atrial fibrillation catheter ablation is limited by the risk of collateral damage to the sinus node and/or the phrenic nerve. Due to its tissue-specificity, we hypothesized the feasibility and safety of pulsed-field ablation (PFA)–based SVC isolation. Methods and results One hundred and five consecutive patients undergoing PFA-based AF catheter ablation were prospectively included. After pulmonary vein isolation (±posterior wall isolation and electrical cardioversion), SVC isolation was performed using a standardized workflow. Acute SVC isolation was achieved in 105/105 (100%) patients after 6 ± 1 applications. Transient phrenic nerve stunning occurred in 67/105 (64%) patients but without phrenic nerve palsy at the end of the procedure and at hospital discharge. Transient high-degree sinus node dysfunction occurred in 5/105 (4.7%) patients, with no recurrence at the end of the procedure and until discharge. At the 3-month follow-up visit, no complication occurred. Conclusion SVC isolation using a pentaspline PFA catheter is feasible and safe.
Clinical Research

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