Journal article
Supportive Family Environments, Genes That Confer Sensitivity, and Allostatic Load Among Rural African American Emerging Adults: A Prospective Analysis
Journal of family psychology, Vol.27(1), pp.22-29
02/2013
DOI: 10.1037/a0027829
PMCID: PMC3390435
PMID: 22468688
Abstract
The purpose of this study was to investigate interactions between exposure to supportive family environments and genetic characteristics, which were hypothesized to forecast variations in allostatic load (AL) in a representative sample of 315 rural African American youths. Data on family environments were gathered when youths were 11-13, and genetic data were collected when they were 16, years of age. Data on AL were obtained at the beginning of emerging adulthood, age 19 years. The data analyses revealed that, as predicted, emerging adults exposed to less supportive family environments across preadolescence manifested higher levels of AL when they carried the short (s) allele at the 5-HTTLPR and an allele of DRD4 with seven or more repeats. This is an E(family environment) × G(5-HTTLPR status) × G(DRD4 status) interaction. These data suggest that African American youths carrying genes that confer sensitivity who are exposed to less supportive family environments may be at greater risk for adverse physical health consequences that AL presages.
Details
- Title: Subtitle
- Supportive Family Environments, Genes That Confer Sensitivity, and Allostatic Load Among Rural African American Emerging Adults: A Prospective Analysis
- Creators
- Gene H Brody - Center for Family Research, University of GeorgiaTianyi Yu - Center for Family Research, University of GeorgiaYi-fu Chen - Center for Family Research, University of GeorgiaSteven M Kogan - Department of Child and Family Development and Center for Family Research, University of GeorgiaGary W Evans - Department of Design and Environmental Analysis and Department of Human Development, Cornell UniversityMichael Windle - Department of Behavioral Sciences and Health Education, Emory UniversityMeg Gerrard - Department of Psychiatry, Dartmouth CollegeFrederick X Gibbons - Department of Psychological and Brain Sciences, Dartmouth CollegeRonald L Simons - Department of Sociology, University of GeorgiaRobert A Philibert - Department of Psychiatry, University of Iowa
- Contributors
- Mark A Whisman (Editor)Nadine J Kaslow (Editor)Steven R. H Beach (Editor)
- Resource Type
- Journal article
- Publication Details
- Journal of family psychology, Vol.27(1), pp.22-29
- Publisher
- American Psychological Association
- DOI
- 10.1037/a0027829
- PMID
- 22468688
- PMCID
- PMC3390435
- ISSN
- 0893-3200
- eISSN
- 1939-1293
- Grant note
- DOI: 10.13039/100000071, name: National Institute of Child Health and Human Development, award: R01HD030588; DOI: 10.13039/100000026, name: National Institute on Drug Abuse, award: P30DA027827
- Language
- English
- Date published
- 02/2013
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Psychiatry
- Record Identifier
- 9984003920002771
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