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Suppression of Experimental Allergic Thyroiditis in Rats Treated with Lithium Chloride
Journal article   Peer reviewed

Suppression of Experimental Allergic Thyroiditis in Rats Treated with Lithium Chloride

B.D JankoviĆ, P Lenert and Kosana MitroviĆ
Immunobiology (1979), Vol.161(5), pp.488-493
1982
DOI: 10.1016/S0171-2985(82)80051-X
PMID: 6284637

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Abstract

Wistar rats were repeatedly injected with 5 mmol of lithium chloride/kg of body weight before and during sensitization with bovine thyroglobulin in complete Freund’s adjuvant. Treatment with lithium chloride significantly suppressed Arthus and delayed skin hypersensitivity reactions to thyroglobulin, and to a lesser extent production of anti-thyroglobulin antibody and experimental allergic thyroiditis.

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